Chemical Properties:
Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer's requirement. Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.Manufacturer Supply Arabinonucleosides Intermediates with High Purity Vidarabine; Ara-A; CAS: 5536-17-4 Arabinofuranosyluracil; Ara-U ; CAS: 3083-77-0 Cytarabine; Ara-C; CAS: 147-94-4Item | Specifications |
Appearance | White or Off-White Crystalline Powder |
Solubility | Colorless Clear |
Purity / Analysis Method | ≥99.0% (HPLC) |
UV Content | ≥98% (on Dry Basis) |
Specific Rotation [a]D20 | -56.0°~-65.0° (C=1 in DMF) |
Adenine | ≤0.50% |
Adenosine | ≤0.50% |
Ara-U | ≤0.50% |
Melting Point | 260.0~265.0℃ |
Heavy Metals | ≤20ppm |
Test Standard | Enterprise Standard |
Storage Temperature | Store at 0~8℃ |
Usage | API; Pharmaceutical Intermediates |
Description:
Specifications:
Package & Storage:
Chemical Name | Vidarabine |
Synonyms | Ara-A; Arabinoadenosine; Adenine 9-β-D-Arabinofuranoside; Vira-A |
CAS Number | 5536-17-4 |
CAT Number | RF-PI220 |
Stock Status | In Stock, Production Scale Up to Tons |
Molecular Formula | C10H13N5O4 |
Molecular Weight | 267.25 |
Brand | Ruifu Chemical |
Advantages:
FAQ:
Application:
Vidarabine (CAS: 5536-17-4), is an antiviral drug which is active against herpes simplex and varicella zoster viruses. Vidarabine (CAS: 5536-17-4) is a neurotransmitter that acts as the preferred endogenous agonist at all adenosine receptor subtypes. Vidarabine (CAS: 5536-17-4) is an inhibitor of A cyclase and DNA Polymerase. Adenine 9-beta-D-arabinofuranoside (ara-A) is a synthetically produced purine nucleoside that is used in cell signaling research. It has commonly been used in anti-viral research with hepadnaviridae and herpes simplex viruses. The nucleoside ara-A interferes with viral DNA synthesis, but only in its active phosphorylated form. Vidarabine (CAS: 5536-17-4) is a nucleoside antibiotic isolated from Streptomyces antibioticus. It has some antineoplastic properties and has broad spectrum activity against DNA viruses in cell cultures and significant antiviral activity against infections caused by a variety of viruses such as the herpes viruses, the VACCINIA VIRUS and varicella zoster virus. Vidarabine (CAS: 5536-17-4) is capable of inhibiting acyclovir-resistant/TK-deficient mutants of HSV and VZV, because it is phosphorylated to its active vidarabine–triphosphate form by cellular kinases and is not dependent for its activation on the viral TK.