Chemical Properties:
Package: Bottle, Aluminum foil bag, 25kg/Cardboard Drum, or according to customer's requirement Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moistureManufacturer Supply Valsartan and Related Intermediates: Valsartan CAS: 137862-53-4 L-Valine Methyl Ester Hydrochloride (H-Val-OMe·HCl) CAS: 6306-52-1| Item | Specifications |
| Appearance | White or Off-White Powder; Odorless, Hygroscopic |
| Identification | IR spectrum of the sample matches the reference standard spectrum |
| Identification | The retention time of the major peak in the chromatogram of the assay preparation corresponds to that of the standard preparation, as obtained in the Assay. |
| Solubility | Soluble in Methanol and Ethanol, Sparingly Soluble in Ethylacetate, Slightly Soluble in Dichloromethane, Insoluble in Water |
| Moisture (K.F) | ≤1.00% |
| Absorbance (420mm) | ≤0.02% (λ=420nm, C=0.05g/ml, L=1cm) |
| Residue on Ignition | ≤0.10% |
| Heavy Metals | ≤10ppm |
| D-Valsartan | ≤1.00% (HPLC) |
| Related Substances (HPLC) | |
| Butyryl-Valsartan | ≤0.20% |
| Benzyl-Valsartan | ≤0.10% |
| Single Unknown Inpurity | ≤0.10% |
| Total Impurities | ≤0.30% (Excluding D-Valsartan) |
| Residual Solvents (GC) | |
| Methanol | ≤3000ppm |
| Ethyl Acetate | ≤5000ppm |
| N,N-Dimethylformamide | ≤880ppm |
| Toluene | ≤890ppm |
| Purity / Analysis Method | >99.0% (HPLC calculated on anhydrous, solvent-free basis) |
| Test Standard | United States Pharmacopoeia (USP) |
| Usage | Active Pharmaceutical Ingredient (API) |
Description:
Specifications:
Package & Storage:
| Chemical Name | Valsartan |
| Synonyms | N-Valeryl-N-[2'-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl]-L-valine |
| CAS Number | 137862-53-4 |
| CAT Number | RF-API32 |
| Stock Status | In Stock, Production Scale Up to Tons |
| Molecular Formula | C24H29N5O3 |
| Molecular Weight | 435.52 |
| Melting Point | 116.0~117.0℃ |
| Stability | Hygroscopic |
| Brand | Ruifu Chemical |
Advantages:
FAQ:
Application:
Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of Valsartan (CAS: 137862-53-4) with high quality. Valsartan is a nonpeptide angiotensin II AT1 receptor antagonist, Antihypertensive, has the potential for high blood pressure and heart failure research. Valsartan’s antihypertensive effects are stronger than those of enalapril and is suitable for treating hypertension, mild to moderate primary hypertension, and especially secondary hypertension caused by renal damage. It can significantly reduce proteinuria for hypertension patients with diabetes or normal liver functions, and it can promote uric acid and urinary sodium to protect the kidney. Valsartan is also suitable for reducing the cardiovascular mortality for high risk patients (left ventricular failure or dysfunction) after experiencing a heart attack.
