Chemical Properties:
Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moistureRuifu Chemical Supply Olmesartan Medoxomil Intermediates With High Quality: 4,5-Dimethyl-1,3-Dioxol-2-One (DMDO) CAS 37830-90-3 4-Chloromethyl-5-Methyl-1,3-Dioxol-2-One (DMDO-Cl) CAS 80841-78-7 Ethyl 4-(1-Hydroxy-1-Methylethyl)-2-Propyl-Imidazole-5-Carboxylate CAS 144689-93-0 Diethyl 2-Propyl-1H-Imidazole-4,5-Dicarboxylate CAS 144689-94-1 Trityl Olmesartan Ethyl Ester CAS 144690-33-5 Trityl Olmesartan Acid CAS 761404-85-7 N2-Trityl Olmesartan Acid CAS 752179-89-8 Trityl Olmesartan Medoxomil CAS 144690-92-6 Olmesartan Medoxomil CAS 144689-63-4| Item | Specifications |
| Appearance | White to Off-White Powder |
| Identification | HPLC; NMR; LC-MS |
| Purity / Analysis Method | >99.0% (HPLC) |
| Water (K.F) | <0.50% |
| Residue on Ignition | <0.10% |
| Related Substances | |
| Individual Impurity | <0.50% |
| Total Impurities | <1.00% |
| Heavy Metals | <10ppm |
| Test Standard | Enterprise Standard |
| Usage | Intermediate of Olmesartan Medoxomil (CAS: 144689-63-4) |
Description:
Specifications:
Package & Storage:
| Chemical Name | Trityl Olmesartan Medoxomil |
| Synonyms | Tritylolmesartan Medoxomil; Triphenyl Methyl Olmesartan; N1-Trityl Olmesartan Medoxomil; Olmesartan Medoxomil EP Impurity D; Olmesartan USP Impurity D; Olmesartan Medoxomil-4; 4-(1-Hydroxy-1-Methylethyl)-2-Propyl-1-[[2'-[2-(Triphenylmethyl)-2H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-1H-Imidazole-5-Carboxylic Acid (5-Methyl-2-oxo-1,3-dioxol-4-yl)methyl Ester; (5-Methyl-2-oxo-1,3-dioxol-4-yl)methyl 4-(2-Hydroxypropan-2-yl)-2-propyl-1-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-Imidazole-5-Carboxylate |
| CAS Number | 144690-92-6 |
| CAT Number | RF-PI1874 |
| Stock Status | In Stock, Production Scale Up to Tons |
| Molecular Formula | C48H44N6O6 |
| Molecular Weight | 800.90 |
| Melting Point | 104.0~106.0℃ |
| Density | 1.26±0.10 g/cm3 |
| Brand | Ruifu Chemical |
Advantages:
FAQ:
Application:
Trityl Olmesartan Medoxomil (CAS: 144690-92-6) is a key intermediate used in the preparation of Olmesartan Medoxomil (CAS: 144689-63-4), an angiotension II receptor antagonist, used in the treatment of hypertension. Olmesartan Medoxomil is a potent and selective angiotensin AT1 receptor inhibitor with IC50 of 66.2 μM. Olmesartan Medoxomil, a prodrug of Olmesartan, is an angiotensin II type 1 receptor (AT1) inhibitor that inhibits negative regulatory feedback on renin secretion, decreasing secretion of aldosterone and resulting in decreased peripheral vascular resistance (vasodilation). It may be used alone or in combination with other antihypertensive agents.
