Trityl Olmesartan Ethyl Ester CAS 144690-33-5 Purity >98.5% (HPLC) Factory

Chemical Name: Trityl Olmesartan Ethyl Ester  CAS: 144690-33-5 Purity: >98.5% (HPLC)  Appearance: White to Off-White Powder   High Quality, Commercial Production E-Mail: alvin@ruifuchem.com

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Chemical Properties:

Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moistureRuifu Chemical Supply Olmesartan Medoxomil Intermediates With High Quality: 4,5-Dimethyl-1,3-Dioxol-2-One (DMDO) CAS 37830-90-3 4-Chloromethyl-5-Methyl-1,3-Dioxol-2-One (DMDO-Cl) CAS 80841-78-7 Ethyl 4-(1-Hydroxy-1-Methylethyl)-2-Propyl-Imidazole-5-Carboxylate CAS 144689-93-0 Diethyl 2-Propyl-1H-Imidazole-4,5-Dicarboxylate CAS 144689-94-1 Trityl Olmesartan Ethyl Ester CAS 144690-33-5 Trityl Olmesartan Acid CAS 761404-85-7 N2-Trityl Olmesartan Acid CAS 752179-89-8 Trityl Olmesartan Medoxomil CAS 144690-92-6 Olmesartan Medoxomil CAS 144689-63-4
Item Specifications
Appearance White to Off-White Powder 
Purity / Analysis Method >98.5% (HPLC)
Water Content (K.F) <0.50%
Residue on Ignition <0.20%
Impurity Ⅰ <0.10% 4-(1-Hydroxy-1-methylpropyl)-2-propyl-1-{[2'-(triphenylmethyl)-1H-tetrazol-5-yl] [1,1'-biphenyl]-4-yl]methyl}-1H-imidazole-5-carboxylic ethyl ester
Impurity Ⅱ <0.10% 4-(1-Methoxy-1-methylethyl)-2-propyl-1-{[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl] [1,1'-biphenyl]-4-yl]methyl}-1H-imidazole-5-carboxylic ethyl ester
Impurity Ⅲ <0.50% 4-Isopropenyl-2-propyl-1-{[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl] [1,1'-biphenyl]-4-yl]methyl}-1H-imidazole-5-carboxylic ethyl ester
Other Maximum Single Impurity <1.00% 
Total Impurities <1.50%
Test Standard Enterprise Standard

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Chemical Name Trityl Olmesartan Ethyl Ester 
Synonyms Olmesartan Ethyl Ester Trityl Impurity; Olmesartan Medoxomil Impurity 30; 4-(1-Hydroxy-1-Methylethyl)-2-propyl-1-[[2'-[1-(Triphenylmethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-1H-Imidazole-5-Carboxylic Acid Ethyl Ester; Ethyl 4-(2-hydroxypropan-2-yl)-2-Propyl-1-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-Imidazole-5-Carboxylate
CAS Number 144690-33-5
CAT Number RF-PI1873
Stock Status In Stock, Production Scale Up to Tons
Molecular Formula C45H44N6O3
Molecular Weight 716.87
Melting Point 161℃
Density 1.18±0.1 g/cm3
Brand Ruifu Chemical

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Application:

Trityl Olmesartan Ethyl Ester (CAS: 144690-33-5) is an impurity of Olmesartan Medoxomil (CAS: 144689-63-4). Olmesartan Medoxomil is an angiotensin II receptor antagonist used to treat high blood pressure, Used as an anti-hypertensive drug. Olmesartan works by blocking the binding of angiotensin II to the AT1 receptors in vascular muscle. By blocking the binding rather than the synthesis of angiotensin II, Olmesartan inhibits the negative regulatory feedback on renin secretion. Olmesartan Medoxomil was launched in the US as Benicar@, an orally administered treatment for hypertension. Olmesartan Medoxomil is rapidly and completely bioactivated by ester hydrolysis to its active metabolite, olmesartan, during absorption from the gastrointestinal tract.

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