Chemical Properties:
Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moistureRuifu Chemical Supply Olmesartan Medoxomil Intermediates With High Quality: 4,5-Dimethyl-1,3-Dioxol-2-One (DMDO) CAS 37830-90-3 4-Chloromethyl-5-Methyl-1,3-Dioxol-2-One (DMDO-Cl) CAS 80841-78-7 Ethyl 4-(1-Hydroxy-1-Methylethyl)-2-Propyl-Imidazole-5-Carboxylate CAS 144689-93-0 Diethyl 2-Propyl-1H-Imidazole-4,5-Dicarboxylate CAS 144689-94-1 Trityl Olmesartan Ethyl Ester CAS 144690-33-5 Trityl Olmesartan Acid CAS 761404-85-7 N2-Trityl Olmesartan Acid CAS 752179-89-8 Trityl Olmesartan Medoxomil CAS 144690-92-6 Olmesartan Medoxomil CAS 144689-63-4| Item | Specifications |
| Appearance | White to Off-White Powder |
| Identification by HPLC | The retention time of the major peak in the chromatogram of the sample corresponds to that of the standard as obtained in purity and related substances |
| Purity / Analysis Method | >98.5% (HPLC) |
| Water (K.F) | <0.50% |
| Residue on Ignition | <0.20% |
| Olmesartan | <1.00% |
| Impurity A | <0.10% 4-(1-Hydroxy-1-methylpropyl)-2-propyl-1-{[2'-[2-(triphenylmethyl)-2H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl}-1H-Imidazole-5-carboxylic acid |
| Impurity B | <0.10% 4-(1-Methoxy-1-methylethyl)-2-propyl-1-{[2'-[2-(triphenylmethyl)-2H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl}-1H-Imidazole-5-carboxylic acid |
| Impurity C | <0.50% 4-Isopropenyl-2-propyl-1-{[2'-[2-(triphenylmethyl)-2H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl}-1H-Imidazole-5-carboxylic acid |
| Other Maximum Single Impurity | <1.00% |
| Total Impurities | <1.50% |
| Heavy Metals (as Pb) | <20ppm |
| Test Standard | Enterprise Standard |
| Usage | Olmesartan Medoxomil (CAS: 144689-63-4) |
Description:
Specifications:
Package & Storage:
| Chemical Name | Trityl Olmesartan Acid |
| Synonyms | TOA; Olmesartan N1-Trityl Impurity; 4-(1-Hydroxy-1-Methylethyl)-2-propyl-1-[[2'-[1-(Triphenylmethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-1H-Imidazole-5-Carboxylic Acid |
| CAS Number | 761404-85-7 |
| CAT Number | RF-PI1875 |
| Stock Status | In Stock, Production Scale Up to Tons |
| Molecular Formula | C43H40N6O3 |
| Molecular Weight | 688.82 |
| Brand | Ruifu Chemical |
Advantages:
FAQ:
Application:
Trityl Olmesartan Acid (CAS: 761404-85-7) is an intermediate or impurity of Olmesartan Medoxomil (CAS: 144689-63-4), an anti-hypertensive drug. Olmesartan Medoxomil (Benicar) is a compound which is hydrolyzed to Olmesartan that is a selective AT1 subtype angiotensin II receptor antagonist. Olmesartan Medoxomil was converted to Olmesartan during absorption from the gastrointestinal tract. Olmesartan is indicated for the treatment of hypertension. It may be used alone or in combination with other antihypertensive agents. Olmesartan Medoxomil exerts its pharmacological functions via blocking the binding of angiotensin II to the AT1 receptors in vascular muscle; it is therefore independent of angiotensin II synthesis pathways, unlike ACE inhibitors.
