Chemical Properties:
Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moistureIntermediates of Pantoprazole Sodium: Pantoprazole Sodium API CAS 138786-67-1 2-(Chloromethyl)-3,4-Dimethoxypyridine Hydrochloride CAS 72830-09-2 5-(Difluoromethoxy)-2-Mercaptobenzimidazole CAS 97963-62-7| Item | Specifications |
| Appearance | White to Off-White Powder |
| Solubility | Free Soluble in Methanol, Ethanol and in Water |
| Test for Sodium | To be Positive |
| IR Spectrum | Complies With Reference Spectrum |
| pH | 9.0~11.5 |
| Moisture Content (K.F) | 4.5~8.0% |
| Related Substances | HPLC Method |
| Major Impurity | ≤0.50% |
| Total Impurities | ≤1.0% |
| Heavy Metals | ≤20ppm |
| Residual Solvents | Meet the Specification |
| Assay(by HPLC) | ≥99.0% |
| Test Standard | Enterprise Standard |
| Usage | API; Proton Pump Inhibitor (PPI) |
Description:
Specifications:
Package & Storage:
| Chemical Name | Pantoprazole Sodium |
| Synonyms | 5-(Difluoromethoxy)-2-(((3,4-Ddimethoxy-2-Pyridinyl)methyl) sulfinyl)-1h-Benzimidazole Sodium |
| CAS Number | 138786-67-1 |
| CAT Number | RF-API107 |
| Stock Status | In Stock, Production Scale Up to Tons |
| Molecular Formula | C16H14F2N3NaO4S |
| Molecular Weight | 405.35 |
| Melting Point | 199.0 to 202.0℃ |
| Brand | Ruifu Chemical |
Advantages:
FAQ:
Application:
Pantoprazole Sodium (CAS: 138786-67-1) is an orally active and proton pump inhibitor (PPI) that suppresses the final step in gastric acid production by covalently binding to the (H+, K+)-ATPase enzyme system at the secretory surface of the gastric parietal cell. Pantoprazole sodium, a substituted benzimidazole, is a potent H+/K+-ATPase inhibitor with an IC50 of 6.8 μM. Pantoprazole sodium improves pH stability and has anti-secretory, anti-ulcer activities. Pantoprazole is used to treat: Short-Term Treatment of Erosive Esophagitis Associated with Gastroesophageal Reflux Disease (GERD) Maintenance of Healing of Erosive Esophagitis Pathological Hypersecretory Conditions Including Zollinger-Ellison (ZE) Syndrome.
