Chemical Properties:
Package: Bottle, Aluminum foil bag, 25kg/Cardboard Drum, or according to customer's requirement. Storage Condition: Store in sealed containers at cool, dry and ventilated warehouse away from incompatible substances. Protect from light and moisture.Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of 5,6,7,8-Tetrahydronaphthalene-1-Carboxylic Acid (CAS: 4242-18-6) with high quality. We can provide COA, worldwide delivery, small and bulk quantities available. If you are interested in this product, please send detailed information includes CAS number, product name, quantity to us. Please contact: alvin@ruifuchem.com| Item | Inspection Standard | Results |
| Appearance | White or Almost White Crystalline Powder | Complied |
| Loss on Drying | <1.00% | 0.67% |
| Residue on Ignition | <0.20% | 0.03% |
| Melting Point | 148.0~152.0℃ | 149.9~150.9℃ |
| Purity (HPLC) | >99.0% (HPLC) | 99.9% |
| Assay | 98.0~101.0% (Neutralization Titration) | 100.9% |
| 1 H NMR Spectrum | Consistent With Structure | |
| Conclusion | This Product by Inspection Accords with the Enterprise Standard | |
| Main Usage | Intermediate of Palonosetron Hydrochloride (CAS: 135729-62-3) | |
Description:
Specifications:
Package & Storage:
| Chemical Name | 5,6,7,8-Tetrahydronaphthalene-1-Carboxylic Acid |
| Synonyms | 5,6,7,8-Tetrahydro-1-Naphthalenecarboxylic Acid; 5,6,7,8-Tetrahydro-Naphthalene-1-Carboxylic Acid; 5,6,7,8-Tetrahydro-1-Naphthoic Acid |
| Stock Status | In Stock, Production Capacity To Tons |
| CAS Number | 4242-18-6 |
| Molecular Formula | C11H12O2 |
| Molecular Weight | 176.22 |
| Melting Point | 148.0~152.0℃ |
| Boiling Point | 336.8±31.0℃ |
| Density | 1.184±0.06 g/cm3 |
| Shipping Condition | Ambient Temperatures |
| COA & MSDS | Available |
| Brand | Ruifu Chemical |
Advantages:
How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals. Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc. Advantages? Superior quality, affordable price, professional services and technical support, fast delivery. Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc. Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers. Factory Audit? Factory audit welcome. Please make an appointment in advance. MOQ? No MOQ. Small order is acceptable. Delivery Time? If within stock, three days delivery guaranteed. Transportation? By Express (FedEx, DHL), by Air, by Sea. Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided. Custom Synthesis? Can provide custom synthesis services to best fit your research needs. Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.FAQ:
Stable Supply: Maintain reasonable stock
Professional Service: One stop purchasing service
Technical Support: Technology solution available
Custom Synthesis Service: Ranged from grams to kilos
Fast Delivery: If within stock, three days delivery guaranteed
High Quality: Established a complete quality assurance system
Application:
5,6,7,8-Tetrahydronaphthalene-1-Carboxylic Acid (CAS: 4242-18-6) is an intermediate used for the preparation of the therapeutically useful antiemetic agent Palonosetron Hydrochloride (CAS: 135729-62-3). Palonosetron Hydrochloride is a drug to inhibit nausea and vomiting, which is a new type highly selective, high-affinity 5-HT3 receptor antagonist that can block the vomiting reflex center peripheral neurons presynaptic 5-HT. Receptor excitement directly affects the central nervous system in 5-HT. Impulse receptor excitement generated by the role of vagal afferent nerve after area, blocking the vagus nerve endings in the gut, preventing signals to 5-HT. Receptor trigger zone can reduce the incidence of nausea and vomiting. Central clinically for the treatment of acute severe emetogenic chemotherapy induced delayed nausea and vomiting. Because of its high curative effect, little side effect, long half-life (about 40 h), small dosage, and so on, it has attracted much attention.Sufficient Capacity: Sufficient facilities and technicians
OEM Package: Custom package and label available