Chemical Properties:
Package: Fluorinated Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement. Storage Condition: Store in sealed containers at cool, dry and ventilated warehouse away from incompatible substances. Protect from light and moisture.Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of tert-Butyl L-Pyroglutamate (H-Pyr-OtBu) (CAS: 35418-16-7) with high quality. Ruifu Chemical supplys a series of amino acids and derivatives. We can provide worldwide delivery, small and bulk quantities available. If you need tert-Butyl L-Pyroglutamate, Please contact: alvin@ruifuchem.com| Hazard Codes | Xi - Irritant | ||
| Risk Statements | 36/38 - Irritating to eyes and skin. | ||
| Safety Statements | 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. | ||
| WGK Germany | 3 | ||
| HS Code | 2922491990 | ||
Description:
Safety Information:
Package & Storage:
| Chemical Name | tert-Butyl L-Pyroglutamate |
| Synonyms | H-Pyr-OtBu; L-Pyr-OtBu; L-Pyroglutamic Acid tert-Butyl Ester; tert-Butyl (S)-5-Oxopyrrolidine-2-Carboxylate; tert-Butyl 5-oxo-L-Prolinate; tert-Butyl (S)-2-Pyrrolidone-5-Carboxylate; (S)-2-Pyrrolidone-5-Carboxylic Acid t-Butyl Ester; tert-Butyl (S)-5-oxo-2-Pyrrolidinecarboxylate; (S)-5-Oxopyrrolidine-2-Carboxylic Acid tert-Butyl Ester |
| Stock Status | In Stock, Production Capacity To Tons |
| CAS Number | 35418-16-7 |
| Molecular Formula | C9H15NO3 |
| Molecular Weight | 185.22 |
| Melting Point | 90.0~95.0℃ |
| Density | 1.099±0.06 g/cm3 |
| Solubility | Soluble in Methanol |
| Storage Temp. | Sealed in Dry, Store at Room Temperature |
| Shipping | Normal |
| COA & MSDS | Available |
| Classification | Amino Acids & Derivatives |
| Brand | Ruifu Chemical |
Advantages:
How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals. Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc. Advantages? Superior quality, affordable price, professional services and technical support, fast delivery. Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc. Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers. Factory Audit? Factory audit welcome. Please make an appointment in advance. MOQ? No MOQ. Small order is acceptable. Delivery Time? If within stock, three days delivery guaranteed. Transportation? By Express (FedEx, DHL), by Air, by Sea. Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided. Custom Synthesis? Can provide custom synthesis services to best fit your research needs. Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.FAQ:
Stable Supply: Maintain reasonable stock
Professional Service: One stop purchasing service
Technical Support: Technology solution available
Custom Synthesis Service: Ranged from grams to kilos
Fast Delivery: If within stock, three days delivery guaranteed
High Quality: Established a complete quality assurance system
Sufficient Capacity: Sufficient facilities and technicians
OEM Package: Custom package and label available
Specifications:
| Items | Inspection Standards | Results |
| Appearance | White or Off-White Crystalline Powder | Conforms |
| Identification | Infrared Absorption Spectrum | Conforms |
| Specific Rotation [α]20/D | +7.5° to +9.5° (C=1, MeOH) | +8.3° |
| Melting Point | 90.0~95.0℃ | Conforms |
| Heavy Metals (as Pb) | <20ppm | <20ppm |
| Loss on Drying | <0.50% | 0.28% |
| Assay / Analysis Method | >98.5% (TLC) | 98.84% |
| Infrared Spectrum | Conforms to Structure | Conforms |
| Proton NMR Spectrum | Conforms to Structure | Conforms |
| Conclusion | This Product by Inspection Accords with the Enterprise Standard | |
| Main Uses | Amino Acids and Derivatives; Pharmaceutical Intermediates | |
Application:
tert-Butyl L-Pyroglutamate (H-Pyr-OtBu) (CAS: 35418-16-7) can be used as pharmaceutical intermediates. Can be used: As a starting material/synthon in the synthesis of angiotensin-converting enzyme inhibitors. In the synthesis of phenanthroindolizidine alkaloids named (+)-tylophorine and antofine. As a starting material in the synthesis of radioligands [18F]IUR-1602 and [18F]IUR-1601, applicable for imaging of P2X7R, a therapeutic target for neuroinflammation.