Chemical Properties:
Package: Fluorinated Bottle, 25kg/Drum, or according to customer's requirement Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moistureShanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of (S)-3-Hydroxy-γ-Butyrolactone (CAS: 7331-52-4) with high quality, commercial production. Ruifu Chemical offers a wide range of chiral compounds. We can provide Certificate of Analysis (COA), worldwide delivery, small and bulk quantities available. Please contact: alvin@ruifuchem.com| Item | Specifications |
| Appearance | Colorless to Pale Yellow Liquid |
| Purity / Analysis Method | >97.0% (GC) |
| Optical Purity | >99.0% e.e |
| Water Content (K.F) | <0.20% |
| 3,4-Di-OH-Butyric Acid | <2.00% |
| Glycolic Acid | <2.00% |
| Specific Rotation [α]20/D | -80.0°～ -84.0° (C=2, Ethanol) |
| Specific Gravity (20/20℃) | 1.3030~1.3090 |
| Refractive Index | n20/D 1.4620~1.4660 |
| Infrared Spectrometry | Conforms to Structure |
| Test Standard | Enterprise Standard |
| Usage | Chiral Building Blocks; Pharmaceutical Intermediates |
Description:
Specifications:
Package & Storage:
| Chemical Name | (S)-3-Hydroxy-γ-Butyrolactone |
| Synonyms | (S)-β-Hydroxy-γ-Butyrolactone; (S)-3-Hydroxy-Gamma-Butyrolactone; (S)-(-)-3-Hydroxy-Gamma-Butyrolactone; S-HGB |
| CAS Number | 7331-52-4 |
| CAT Number | RF-CC344 |
| Stock Status | In Stock, Production Scale Up to Tons |
| Molecular Formula | C4H6O3 |
| Molecular Weight | 102.09 |
| Brand | Ruifu Chemical |
Advantages:
FAQ:
Application:
(S)-3-Hydroxy-γ-Butyrolactone (CAS: 7331-52-4) is an important intermediate in organic synthesis and an important chiral pool. It is mainly used in the synthesis of some natural products and some bioactive chiral drugs or antibiotic chiral drugs. For example, it is a key intermediate in synthesis of nerve regulator (R)-GABOB and brain metabolic accelerant S-oxiracetam (S-ORC). It can be deoxidized to (S)-(+)-3-Hydroxytetrahydrofuran which is an important intermediate of anti-AIDS drugs. It is also used in the synthesis of S(-)-3-Hydroxy-4-Bromobutyric Acid which is a potential stabilizer. (S)-3-Hydroxy-γ-Butyrolactone is widely used in the pharmaceutical industry as a chiral building block for the statin class of cholesterol-reducing drugs such as Crestor and Lipitor, as well as the antibiotic Zyvox, and the antihyperlipidemic medication Zetia.
