Chemical Properties:
Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement. Storage Condition: Store in sealed containers at cool and dry (≤-20℃) warehouse away from incompatible substances. Protect from light and moisture. Shipping: Deliver to worldwide by FedEx / DHL Express. Provide fast and reliable delivery. Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of 3-(Diethoxyphosphoryloxy)-1,2,3-Benzotriazin-4(3H)-one (DEPBT) (CAS: 165534-43-0) with high quality. Ruifu Chemical supplys a series of protecting reagents and coupling reagents. Ruifu can provide worldwide delivery, competitive price, small and bulk quantities available. Purchase DEPBT, Please contact: alvin@ruifuchem.comDescription:
Package/Storage/Shipping:
| Chemical Name | 3-(Diethoxyphosphoryloxy)-1,2,3-Benzotriazin-4(3H)-one |
| Synonyms | DEPBT; Diethyl 3,4-Dihydro-4-oxo-1,2,3-Benzotriazin-3-yl Phosphate; Diethyl (4-oxobenzo[d][1,2,3]triazin-3(4H)-yl) Phosphate |
| Stock Status | In Stock, Mass Production |
| CAS Number | 165534-43-0 |
| Molecular Formula | C11H14N3O5P |
| Molecular Weight | 299.22 g/mol |
| Melting Point | 68.0~78.0℃ |
| Density | 1.45±0.10 g/cm3 |
| Sensitive | Hygroscopic. Moisture Sensitive, Light Sensitive |
| Solubility in Ethylacetate | Almost Transparency |
| Storage Temp. | Cool & Dry Place (≤-20℃, Away from Light) |
| COA & MSDS | Available |
| Category | Coupling Reagents |
| Brand | Ruifu Chemical |
Advantages:
How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals. Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc. Advantages? Superior quality, affordable price, professional services and technical support, fast delivery. Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc. Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers. Factory Audit? Factory audit welcome. Please make an appointment in advance. MOQ? No MOQ. Small order is acceptable. Delivery Time? If within stock, three days delivery guaranteed. Transportation? By Express (FedEx, DHL), by Air, by Sea. Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided. Custom Synthesis? Can provide custom synthesis services to best fit your research needs. Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.FAQ:
Stable Supply: Maintain reasonable stock
Professional Service: One stop purchasing service
Technical Support: Technology solution available
Custom Synthesis Service: Ranged from grams to kilos
Fast Delivery: If within stock, three days delivery guaranteed
High Quality: Established a complete quality assurance system
Sufficient Capacity: Sufficient facilities and technicians
OEM Package: Custom package and label available
Specifications:
| Items | Inspection Standards | Results |
| Appearance | White to Off-White Crystalline Powder | Complies |
| Melting Point | 68.0~78.0℃ | 72.5~73.1℃ |
| Loss on Drying | <0.50% | 0.13% |
| Residue on Ignition | <0.20% | 0.12% |
| Purity / Analysis Method | >99.0% (HPLC) | 99.8% |
| Solubility in EtOAC | Solution Transparent | Complies |
| Infrared Spectrum | Conforms to Structure | Complies |
| 1 H NMR Spectrum | Conforms to Structure | Complies |
| Conclusion | The product has been tested & complies with the specifications | |
165534-43-0 - Risk and Safety:
Application:
Hazard Symbols Xi - Irritant Risk Codes 36/37/38 - Irritating to eyes, respiratory system and skin. Safety Description S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. WGK Germany 33-(Diethoxyphosphoryloxy)-1,2,3-Benzotriazin-4(3H)-one (DEPBT) (CAS: 165534-43-0) is a peptide coupling reagent used in peptide synthesis. It shows remarkable resistance to racemization. DEPBT is a coupling reagent that facilitates amide bond formation and also resists racemization. It has been shown to be more effective than phosphonium and uronium coupling reagents. DEPBT, the highly efficient reagent for amide bond formation in synthesizing complex molecules and for peptide cyclization. Compatible for a solution and solid-phase synthesis. DEPBT is compatible with solution and SPPS. DEPBT is an organophosphorous coupling reagent used in peptide chemistry. DEPBT is efficient in the synthesis of linear, cyclic and sterically hindered peptides, in solution and solid phase synthesis, achieving high yields with fast kinetics and remarkable retention of configuration. DEPBT can be easily synthesised, is a crystalline phosphate stable for months and shows often better performances than the commonly used phosphonium and uronium salts. Notably, in presence of DEPBT it is not necessary to protect the hydroxyl group in the amino acids (such as tyrosine, serine, and threonine) and the imidazole group of histidine. Therefore, DEPBT can be employed in the synthesis of amino alcohols and N-glycopeptides. DEPBT finds application in the synthesis of numerous bioactive peptides and complex natural products.