Chemical Properties:
Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer's requirement Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moistureCommercial Supply (CAS: 177036-94-1) Related Intermediates: CAS: 177036-94-1 Methyl 2-Hydroxy-3-Methoxy-3,3-Diphenylpropanoate CAS: 178306-47-3 2-Hydroxy-3-Methoxy-3,3-Diphenylpropanoic Acid CAS: 178306-51-9 (S)-2-Hydroxy-3-Methoxy-3,3-Diphenylpropionic Acid CAS: 178306-52-0 L-Proline Methyl Ester Hydrochlorid CAS: 2133-40-6 4,6-Dimethyl-2-(Methylsulfonyl)pyrimidine CAS: 35144-22-0| Item | Specifications |
| Appearance | Off-White to White Powder |
| Purity | ≥99.0% |
| Moisture (K.F) | ≤0.50% |
| Any Single Impurity | ≤0.50% |
| Total Impurities | ≤1.00% |
| Isomer | ≤0.10% |
| Melting Point | 115.0～125.0℃ |
| Specific Rotation | +9.5° ~ +11.5° (C=1, EtOH) |
| Test Standard | Enterprise Standard |
| Usage | Intermediate of API (CAS: 177036-94-1) |
Description:
Specifications:
Package & Storage:
| Chemical Name | (S)-2-Hydroxy-3-Methoxy-3,3-Diphenylpropionic Acid |
| Synonyms | (S)-2-Hydroxyl-3-Methoxy-3,3-Diphenylpropanoic Acid |
| CAS Number | 178306-52-0 |
| CAT Number | RF-PI162 |
| Stock Status | In Stock, Production Scale Up to Hundreds of Kilograms |
| Molecular Formula | C16H16O4 |
| Molecular Weight | 272.30 |
| Density | 1.248 |
| Brand | Ruifu Chemical |
Advantages:
FAQ:
Application:
(S)-2-Hydroxy-3-Methoxy-3,3-Diphenylpropionic Acid (CAS: 178306-52-0) is the intermediate of API (CAS: 177036-94-1). (CAS: 177036-94-1) is a selective endothelin-A (ETA) receptor antagonist introduced for the oral treatment of patients with pulmonary arterial hypertension (PAH), to improve exercise capacity and delay clinical worsening. PAH is a rare disease of the small pulmonary arteries characterized by vascular proliferation and remodeling, resulting in a progressive increase in pulmonary vascular resistance and pulmonary arterial pressure, and ultimately, right ventricular failure and premature death. Early symptoms of PAH include gradual onset of shortness of breath, fatigue, palpitation, edema, and fainting. API (CAS: 177036-94-1) is a nonpeptide endothelin ETA receptor antagonist and antihypertensive.
