(S)-3-[1-(Dimethylamino)ethyl]phenol CAS 139306-10-8 Rivastigmine Tartrate Intermediate Purity >99.0% (GC)

(S)-3-[1-(Dimethylamino)ethyl]phenol CAS: 139306-10-8 Purity: >99.0% (GC) Appearance: Off-White to Light Yellow Powder Intermediate of Rivastigmine Tartrate (CAS: 129101-54-8) Contact: Dr. Alvin Huang Mobile/Wechat/WhatsApp: +86-15026746401 E-Mail: alvin@ruifuchem.com

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Chemical Properties:

Package: Fluorinated Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement. Storage Condition: Keep the container tightly closed and store in a cool, dry and well-ventilated warehouse away from incompatible substances. Protect from light and moisture. Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery. Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of (S)-3-[1-(Dimethylamino)ethyl]phenol (CAS: 139306-10-8) with high quality, intermediate of Rivastigmine Tartrate (CAS: 129101-54-8). Ruifu Chemical can provide worldwide delivery, competitive price, excellent service, small and bulk quantities available. Purchase (S)-3-[1-(Dimethylamino)ethyl]phenol, Please contact: alvin@ruifuchem.com

Description:

Package/Storage/Shipping:

Chemical Name (S)-3-[1-(Dimethylamino)ethyl]phenol 
Synonyms 3-[(1S)-1-(Dimethylamino)ethyl]phenol; NAP 226-90; Rivastigmine Metabolite; Rivastigmine Phenol Impurity
Impurity  Rivastigmine EP Impurity A; Rivastigmin USP Related Compound C 
Stock Status In Stock, Commercial Production  
CAS Number 139306-10-8 
Molecular Formula C10H15NO
Molecular Weight 165.24 g/mol
Melting Point 117.0 to 121.0℃ 
Specific Rotation [a]20/D -53.0° to -58.0° (C=1, MeOH)
COA & MSDS Available
Origin Shanghai, China
Category   Intermediate of Rivastigmine Tartrate (CAS: 129101-54-8)  
Brand Ruifu Chemical

Advantages:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com  15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals. Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc. Advantages? Superior quality, affordable price, professional services and technical support, fast delivery. Quality AssuranceStrict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc. SamplesMost products provide free samples for quality evaluation, shipping cost should be paid by customers. Factory AuditFactory audit welcome. Please make an appointment in advance. MOQ? No MOQ. Small order is acceptable. Delivery Time? If within stock, three days delivery guaranteed. TransportationBy Express (FedEx, DHL), by Air, by Sea. Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided. Custom SynthesisCan provide custom synthesis services to best fit your research needs. Payment TermsProforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

FAQ:

Stable Supply: Maintain reasonable stock    

Professional Service: One stop purchasing service

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

Fast Delivery: If within stock, three days delivery guaranteed

High Quality: Established a complete quality assurance system

Sufficient Capacity: Sufficient facilities and technicians

OEM Package: Custom package and label available

Specifications:

Items Inspection Standards Results
Appearance Off-White to Light Yellow Powder Complies      
Melting Point 117.0 to 121.0℃ Complies 
Purity / Analysis Method >99.0% (GC)  99.55%
Isomer Assay <0.50% Complies 
Water by Karl Fischer  <0.50% 0.23% 
Residue on Ignition <0.20% 0.09% 
Max. Single Impurity <0.50% Complies 
Total Impurities <1.00% 0.45%
1H NMR Spectrum Consistent with Structure Complies
Conclusion The product has been tested and complies with the given specifications

139306-10-8 - Risk and Safety:

139306-10-8 - Application:

Risk Codes R36 - Irritating to the eyes R43 - May cause sensitization by skin contact Safety Description S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. HS Code 2922299090(S)-3-[1-(Dimethylamino)ethyl]phenol (CAS: 139306-10-8), is a S-Enantiomer metabolite of Rivastigmine that is formed by hydrolysis. Intermediate / Impurity of Rivastigmine Tartrate (CAS: 129101-54-8). Rivastigmine (Exelon) is approved to prevent or slow the symptoms of mild to moderate AD or mild to moderate Parkinson's dementia. Rivastigmine is a parasympathomimetic or cholinergic agent for the treatment of mild to moderate dementia of the Alzheimer's type and dementia due to Parkinson's disease. The drug can be administered orally or via a transdermal patch; the latter form reduces the prevalence of side effects,which typically include nausea and vomiting.The drug is eliminated through the urine, and appears to have relatively few drug-drug interactions.

Rivastigmine Tartrate Intermediates:

Rivastigmine Tartrate CAS 129101-54-8                                  
3-[1-(Dimethylamino)ethyl]phenol CAS 105601-04-5
(S)-3-[1-(Dimethylamino)ethyl]phenol CAS 139306-10-8
N-Ethyl-N-Methylcarbamoyl Chloride CAS 42252-34-6
Bis(4-Nitrophenyl) Carbonate (NPC) CAS 5070-13-3

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