Chemical Properties:
Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moistureShanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of Rifamycin S (CAS: 13553-79-2) with high quality. We can provide COA, worldwide delivery, small and bulk quantities available. Please contact: alvin@ruifuchem.com| Item | Specifications |
| Appearance | Yellow or Orange Yellow Crystalline Powder |
| Loss on Drying | ≤3.00%（4h 100℃) |
| Residue on Ignition | ≤0.50% |
| Related Substances | |
| Rifamycin-O | ≤0.50% |
| Rifamycin-B | ≤0.50% |
| One Peak | ≤1.00% |
| Total Impurities | ≤2.50% |
| Purity / Analysis Method | >97.5% (HPLC) |
| Infrared Spectrum | Conforms to Structure |
| Proton NMR Spectrum | Conforms to Structure |
| Test Standard | Enterprise Standard |
| Shelf Life | 24 Months From Manufacture Date if Stored Properly |
| Usage | A Key Intermediate for the Synthesis of Rifamycin Medicines |
Description:
Specifications:
Package & Storage:
| Chemical Name | Rifamycin S |
| Synonyms | 1,4-Dideoxy-1,4-Dihydro-1,4-Dioxorifamycin; Rifaximin EP Impurity E |
| CAS Number | 13553-79-2 |
| CAT Number | RF-PI2058 |
| Stock Status | In Stock, Production Capacity 500MT/Year |
| Molecular Formula | C37H45NO12 |
| Molecular Weight | 695.76 |
| Sensitivity | Heat Sensitive |
| Specific Rotation [α]20/D | +451.0°~+500.0° (C=0.1 in MeOH) |
| Melting Point | 201℃ |
| Brand | Ruifu Chemical |
Advantages:
FAQ:
Application:
Rifamycin S (CAS: 13553-79-2) is a key intermediate for the synthesis of rifamycin medicines. Rifamycin S is a semi-synthetic antibiotic. Rifamycin S is a quinone and an antibiotic agnet against Gram-positive bacteria (including MRSA). Rifamycin S is the oxidized forms of a reversible oxidation-reduction system involving two electrons. Rifamycin S generates reactive oxygen species (ROS) and inhibits microsomal lipid peroxidation. Rifamycin S can be used for tuberculosis and leprosy. The rifamycins are a group of chemically related antibioticsobtained by fermentation from cultures of Streptomycesmediterranei. They belong to a class of antibiotics called theansamycins that contain a macrocyclic ring bridged acrosstwo nonadjacent positions of an aromatic nucleus. The rifamycins and many of their semisynthetic derivativeshave a broad spectrum of antimicrobial activity. They are most notably active against Gram-positive bacteriaand M. tuberculosis. However, they are also active againstsome Gram-negative bacteria and many viruses. Rifampin, asemisynthetic derivative of Rifamycin B, was released as anantitubercular agent in the United States in 1971. A secondsemisynthetic derivative, rifabutin, was approved in 1992 forthe treatment of atypical mycobacterial infections.
