Chemical Properties:
Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer's requirement. Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.Manufacturer Commercial Supply Remdesivir and Related Intermediates with High Quality Remdesivir CAS 1809249-37-3 2-Ethyl-1-butanol CAS 97-95-0 Trimethylsilyl Cyanide CAS 7677-24-9 4-Nitrophenol CAS 100-02-7 2-Ethylbutyl ((S)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate CAS 1911578-98-7 N-[(S)-(4-nitrophenoxy)phenoxyphosphinyl]-L-Alanine 2-ethylbutyl ester CAS 1354823-36-1 (S)-2-Ethylbutyl 2-Aminopropanoate Hydrochloride CAS 946511-97-3 Remdesivir Metabolite (GS-441524) CAS 1191237-69-0 Remdesivir N-2 Intermediate CAS 1191237-80-5 2,3,5-Tri-O-benzyl-D-ribonolactone CAS 55094-52-5 7-Bromopyrrolo[2,1-f][1,2,4]triazin-4-amine CAS 937046-98-5 Pyrrolo[1,2-F][1,2,4]Triazin-4-Amine CAS 159326-68-8 4-Amino-7-iodopyrrolo[2,1-f][1,2,4]triazine CAS 1770840-43-1| Item | Specifications |
| Appearance | White to Almost White Powder |
| Purity | ≥99.0% |
| Alpha-Isomer | ≤0.30% |
| O-Bn Derivative | ≤0.30% |
| N-Bn Derivative | ≤0.30% |
| Maximum Single Impurity | ≤0.30% |
| Loss on Drying | ≤1.0% |
| Residue on Ignition | ≤0.50% |
| Heavy Metals | ≤20ppm |
| Arsenic | ≤2ppm |
| Test Standard | Enterprise Standard |
| Usage | Intermediate of Remdesivir (CAS 1809249-37-3); COVID-19 |
Description:
Specifications:
Package & Storage:
| Chemical Name | (2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-Dihydroxy-5-(Hydroxymethyl)tetrahydrofuran-2-Carbonitrile |
| Synonyms | GS-441524; Remdesivir Metabolite; Remdesivir Intermediate; Nucleosid of Remdesivir; EVO984; Remdesivir O-Desphosphate Analogue; Remdesivir Related Compound 6 Impurity |
| CAS Number | 1191237-69-0 |
| CAT Number | RF-PI299 |
| Stock Status | In Stock, Production Scale Up to Hundreds of Kilograms |
| Molecular Formula | C12H13N5O4 |
| Molecular Weight | 291.26 |
| Solubility | Soluble in DMSO |
| Storag | Cool Dry Place |
| Shipping Condition | Shipped Under Ambient Temperature |
| Brand | Ruifu Chemical |
Advantages:
FAQ:
Application:
Remdesivir nucleoside analogue (GS-441524, CAS 1191237-69-0) is an essential building block to the synthesis of Remdesivir triphosphate (1355149-45-9) and Remdesivir (1809249-37-3). GS-441524 is a nucleoside analogue antiviral drug which was developed by Gilead Sciences. This phosphorus analog is mainly an active compound in the treatment of Ebola and COVID-19. It is the main plasma metabolite of the antiviral prodrug remdesivir, and has a half-life of around 24 hours in human patients. Remdesivir and GS-441524 were both found to be effective in vitro against feline coronavirus strains responsible for feline infectious peritonitis (FIP), a lethal systemic disease affecting domestic cats.
