Remdesivir Intermediate CAS 946511-97-3 COVID-19 (S)-2-Ethylbutyl 2-Aminopropanoate Hydrochloride

Name: (S)-2-Ethylbutyl 2-Aminopropanoate Hydrochloride Synonyms: L-Alanine 2-Ethylbutyl Ester Hydrochloride  CAS: 946511-97-3 Appearance: White to Almost White Powder Purity: ≥99.0% Intermediate of Remdesivir (CAS 1809249-37-3) for the treatment of COVID-19 High Quality, Commercial Production Inquiry: alvin@ruifuchem.com

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Chemical Properties:

Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer's requirement. Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.Manufacturer Commercial Supply Remdesivir and Related Intermediates with High Quality Remdesivir CAS 1809249-37-3 2-Ethyl-1-butanol CAS 97-95-0 Trimethylsilyl Cyanide CAS 7677-24-9 4-Nitrophenol CAS 100-02-7 2-Ethylbutyl ((S)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate CAS 1911578-98-7 N-[(S)-(4-nitrophenoxy)phenoxyphosphinyl]-L-Alanine 2-ethylbutyl ester CAS 1354823-36-1 (S)-2-Ethylbutyl 2-Aminopropanoate Hydrochloride CAS 946511-97-3 Remdesivir Metabolite (GS-441524) CAS 1191237-69-0 Remdesivir N-2 Intermediate CAS 1191237-80-5 2,3,5-Tri-O-benzyl-D-ribonolactone CAS 55094-52-5 7-Bromopyrrolo[2,1-f][1,2,4]triazin-4-amine CAS 937046-98-5 Pyrrolo[1,2-F][1,2,4]Triazin-4-Amine CAS 159326-68-8 4-Amino-7-iodopyrrolo[2,1-f][1,2,4]triazine CAS 1770840-43-1
Item Specifications
Appearance White to Almost White Powder 
Loss on Drying ≤1.0%
Single Impurity ≤0.50%
Total Impurities ≤1.0%
Heavy Metals ≤20ppm
Purity ≥99.0% 
Test Standard Enterprise Standard
Usage Intermediate of Remdesivir (CAS 1809249-37-3); COVID-19

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Specifications:

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Chemical Name (S)-2-Ethylbutyl 2-Aminopropanoate Hydrochloride
Synonyms Remdesivir Intermediate; L-Alanine 2-Ethylbutyl Ester Hydrochloride; Remdesivir Amino Ester Compound; Remdesivir Related Compound 8; Remdesivir Impurity 8
CAS Number 946511-97-3
CAT Number RF-PI298
Stock Status In Stock, Production Scale Up to Hundreds of Kilograms
Molecular Formula C9H20ClNO2
Molecular Weight 209.71
Melting Point 75.0 to 79.0℃
Sensitive Hygroscopic
Brand Ruifu Chemical

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Application:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of (S)-2-Ethylbutyl 2-Aminopropanoate Hydrochloride (CAS 946511-97-3), it's typically used for the preparation of Remdesivir (CAS 1809249-37-3). Remdesivir, also known as GS-5734, is a novel antiviral drug in the class of nucleotide analogs developed by Gilead Sciences, with effective antiviral activity( EC50s of 74 nM for SARS-CoV and MERS-CoV in HAE cells). In February 2020 Remdesivir was being studied for experimental treatment of the emergent COVID-19 (novel coronavirus) disease.

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