Chemical Properties:
Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer's requirement. Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.Manufacturer Commercial Supply Remdesivir and Related Intermediates with High Quality Remdesivir CAS 1809249-37-3 2-Ethyl-1-butanol CAS 97-95-0 Trimethylsilyl Cyanide CAS 7677-24-9 4-Nitrophenol CAS 100-02-7 2-Ethylbutyl ((S)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate CAS 1911578-98-7 N-[(S)-(4-nitrophenoxy)phenoxyphosphinyl]-L-Alanine 2-ethylbutyl ester CAS 1354823-36-1 (S)-2-Ethylbutyl 2-Aminopropanoate Hydrochloride CAS 946511-97-3 Remdesivir Metabolite (GS-441524) CAS 1191237-69-0 Remdesivir N-2 Intermediate CAS 1191237-80-5 2,3,5-Tri-O-benzyl-D-ribonolactone CAS 55094-52-5 7-Bromopyrrolo[2,1-f][1,2,4]triazin-4-amine CAS 937046-98-5 Pyrrolo[1,2-F][1,2,4]Triazin-4-Amine CAS 159326-68-8 4-Amino-7-iodopyrrolo[2,1-f][1,2,4]triazine CAS 1770840-43-1| Item | Specifications |
| Appearance | White to Almost White Powder |
| Identification | IR, HPLC |
| Loss on Drying | ≤1.0% |
| Single Impurity | ≤0.50% |
| Heavy Metals | ≤20ppm |
| Purity | ≥98.0% |
| Test Standard | Enterprise Standard |
| Usage | Intermediate of Remdesivir (CAS 1809249-37-3); COVID-19 |
Description:
Specifications:
Package & Storage:
| Chemical Name | N-[(S)-(4-nitrophenoxy)phenoxyphosphinyl]-L-Alanine 2-ethylbutyl ester |
| Synonyms | Remdesivir Intermediate; Remdesivir Side Chain; Remdesivir p-NitroPhenoxy L-Alanine Impurity; Remdesivir Impurity 4; Remdesivir-002; (S)-2-Ethylbutyl 2-(((S)-(4-nitrophenoxy)(phenoxy)-phosphoryl)-amino)propanoate |
| CAS Number | 1354823-36-1 |
| CAT Number | RF-PI297 |
| Stock Status | In Stock, Production Scale Up to Hundreds of Kilograms |
| Molecular Formula | C21H27N2O7P |
| Molecular Weight | 450.42 |
| Brand | Ruifu Chemical |
Advantages:
FAQ:
Application:
N-[(S)-(4-nitrophenoxy)phenoxyphosphinyl]-L-Alanine 2-ethylbutyl ester (CAS 1354823-36-1, also known as Remdesivir Impurity 4) is a phosphoramidate sidechain typically used for the preparation of Remdesivir (CAS 1809249-37-3, GS-5734), which is a novel antiviral investigational drug originally for the treatment of Ebola virus disease and Marburg virus infections and has subsequently also been found to show antiviral activity against coronaviruses (e.g. SARS-Cov-2/Covid-19). During the outbreak of the new Coronavirus Disease 2019 (COVID-19), Remdesivir (CAS 1809249-37-3) is one of the COVID-19 related research products. Remdesivir, sold under the brand name Veklury, is a broad-spectrum antiviral medication developed by the biopharmaceutical company Gilead Sciences. It is administered via injection into a vein. During the COVID-19 pandemic, Remdesivir was approved or authorized for emergency use to treat COVID-19 in around 50 countries. Updated guidelines from the World Health Organization in November 2020 include a conditional recommendation against the use of Remdesivir for the treatment of COVID-19.
