Chemical Properties:
Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moistureRuifu Chemical Supply Rabeprazole Sodium Intermediates Rabeprazole Sodium CAS 117976-90-6 Rabeprazole Hydroxy Compound CAS 675198-19-3 Rabeprazole Chloride Compound CAS 153259-31-5| Item | Specifications |
| Appearance | Yellowish to Off-White Crystalline Powder |
| Assay / Analysis Method | >99.5% (HPLC) |
| Loss on Drying | <0.50% |
| Water (K.F) | <0.50% |
| Residue on Ignition | <0.20% |
| Any Single Impurity | <0.50% |
| Total Impurities | <0.50% |
| Heavy Metals | <20ppm |
| Test Standard | Enterprise Standard |
| Usage | Intermediate of Rebeprazole Sodium (CAS: 117976-90-6) |
Description:
Specifications:
Package & Storage:
| Chemical Name | 2-Chloromethyl-3-Methyl-4-(3-Methoxypropoxy)pyridine Hydrochloride |
| Synonyms | Rabeprazole Chloride Compound; Rabeprazole Chloro Compound; Rabeprazole 2-Chloromethyl Impurity; 4-(3-Methoxypropoxy)-2-(Chloromethyl)-3-Methylpyridine Hydrochlorid |
| CAS Number | 153259-31-5 |
| CAT Number | RF-PI1918 |
| Stock Status | In Stock, Production Scale Up to Tons |
| Molecular Formula | C11H17Cl2NO2 |
| Molecular Weight | 266.16 |
| Melting Point | 113.0~115.0℃ |
| Brand | Ruifu Chemical |
Advantages:
FAQ:
Application:
2-Chloromethyl-3-Methyl-4-(3-Methoxypropoxy)pyridine Hydrochloride, Rabeprazole Chloride Compound (CAS: 153259-31-5) is an intermediate of Rebeprazole Sodium (CAS: 117976-90-6). Rabeprazole Sodium is a anti-ulcer disease drug belonging to proton pump inhibitor and is the sodium salt form of Rabeprazole. The Japanese company Eisai had successfully developed it for the first time with the trade name being “Bolite”. The function of the proton pump inhibitors is reducing the gastric acid secretion so that the lesion site can be stable in order to achieving the effect of curing gastric and duodenal ulcers and stomach-esophageal reflux disease. Clinically it is majorly used for the treatment of acid-related diseases such as stomach and duodenal ulcers, peptic ulcer, gastroesophageal reflux disease and zollinger-ellison syndrome. Rabeprazole is a kind of benzimidazole-substituted compounds. It inhibits the secretion of gastric acid through forming bond with the cytoplasmic proton pump in the gastric cavity wall. This product can specifically inhibit the effect of the adenosine triphosphatase that is the key enzyme during the production of stomach acid. It has inhibitory effect on both basal gastric acid and the gastric acid secretion caused by the stimulation.
