Chemical Properties:
Package: Bottle, Aluminium foil bag, Cardboard Drum, 25kg/Drum, or according to customer's requirement. Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.Manufacturer Supply Atazanavir Related Intermediates Moc-L-Tert-Leucine CAS 162537-11-3 4-(2-Pyridyl)benzaldehyde CAS 127406-56-8 (2S,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane CAS 98737-29-2 (2R,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane CAS 98760-08-8 tert-Butyl 2-(4-(pyridin-2-yl)benzyl)hydrazinecarboxylate CAS 198904-85-7 Atazanavir CAS 198904-31-3 Atazanavir Sulfate CAS 229975-97-7 High Quality, Commercial Production| Item | Specifications |
| Appearance | White to Off-White Crystalline Powder |
| Identification | The identification is confirmed by HPLC RT |
| Solubility | Soluble in Methanol |
| Specific Rotation | -10°~ -20° |
| Water (K.F) | ≤0.50% |
| Residue on Ignition | ≤0.20% |
| Related Substances | |
| Impurity (RRT0.97) | ≤0.30% |
| Any Single Impurity | ≤0.30% |
| Total Impurities | ≤1.0% |
| Heavy Metals | ≤20ppm |
| Purity / Analysis Method | ≥99.0% (HPLC) |
| Enantiomeric Purity | ≤0.30% |
| Test Standard | Enterprise Standard |
| Usage | Intermediate of Atazanavir (CAS 198904-31-3) HIV-1 Protease Inhibitor |
Description:
Specifications:
Package & Storage:
| Chemical Name | (2R,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane |
| Synonyms | (2R,3S)-3-(tert-Boc)amino-1,2-epoxy-4-phenylbutane; (2R,3S)-3-(tert-Butoxycarbonyl)amino-1,2-epoxy-4-phenylbutane; Atazanavir Intermediate; Atazanavir Impurity C; threo-N-Boc-L-phenylalanine epoxide |
| CAS Number | 98760-08-8 |
| CAT Number | RF-PI288 |
| Stock Status | In Stock, Production Scale Up to Tons |
| Molecular Formula | C15H21NO3 |
| Molecular Weight | 263.34 |
| Shipping Condition | Under Ambient Temperature |
| Brand | Ruifu Chemical |
Advantages:
FAQ:
Application:
Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of (2R,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane (CAS 98760-08-8) with high quality, an intermediate of Atazanavir (CAS 198904-31-3) and Atazanavir Sulfate (CAS 229975-97-7). Atazanavir is a novel azapeptide HIV protease inhibitor (PI). Atazanavir is an inhibitor of human immunodeficiency virus type 1 (HIV-1) protease, an enzyme that is essential for the processing of Gag and Gag-Pol polyproteins into structural and enzymatic proteins required for viral replication. It has a similar pharmacophore motif to the other six widely marketed HIV protease inhibitors, most of which are based upon a hydroxyethylamine template. Uniquely, it possesses an aza-peptide motif but maintains many similar pharmacophore elements including lipophilic moieties that presumably bind to S2, S1, S′1, and S′2 positions.
