Chemical Properties:
Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer's requirement. Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.Manufacturer Supply; High Purity and Competitive Price Shanghai Ruifu Chemical Co., Ltd. Commercial Supply Chiral Compounds: (R)-(-)-3-Pyrrolidinol Hydrochloride CAS: 104706-47-0 (S)-3-Hydroxypyrrolidine hydrochloride CAS: 122536-94-1 Intermediate of Panipenem (CAS 87726-17-8) and Darifenacin hydrobromide (CAS 133099-07-7)| Item | Specifications |
| Appearance | Off-White to Pale Brown Crystalline Powder |
| Purity / Analysis Method | ≥99.7% (GC) |
| Chiral Purity | ≥99.7% e.e |
| Residue on Ignition | ≤0.50% |
| Specific Rotation [α]D20 | -6.5°~ -8.5° (C=3.5 CH3OH) |
| Any Individual Impurity | ≤0.20% |
| Total impurities | ≤0.30% |
| Test Standard | Enterprise Standard |
| Usage | Pharmaceutical Intermediates; Chiral Compounds |
Description:
Specifications:
Package & Storage:
| Chemical Name | (R)-(-)-3-Pyrrolidinol Hydrochloride |
| Synonyms | (R)-(-)-3-Hydroxypyrrolidine Hydrochloride; (R)-(-)-3-Hydroxypyrrolidine-HCl |
| CAS Number | 104706-47-0 |
| CAT Number | RF-CC102 |
| Purity / Analysis Method | ≥98.0% (GC) |
| Stock Status | In Stock, Production Scale Up to Tons |
| Molecular Formula | C4H10ClNO |
| Molecular Weight | 123.58 |
| Melting Point | 107.0 ~ 111.0 °C |
| Solubility in Water | Almost Transparency |
| Brand | Ruifu Chemical |
Advantages:
FAQ:
Stable Supply: Maintain reasonable stock
Professional Service: One stop purchasing service
Technical Support: Technology solution available
Custom Synthesis Service: Ranged from grams to kilos
Fast Delivery: If within stock, three days delivery guaranteed
High Quality: Established a complete quality assurance system
Application:
Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of (R)-(-)-3-Pyrrolidinol Hydrochloride (CAS: 104706-47-0) with high quality, widely used in organic synthesis, synthesis of pharmaceutical intermediates and Active Pharmaceutical Ingredient (API) synthesis. (R)-(-)-3-Pyrrolidinol Hydrochloride (CAS: 104706-47-0) is an intermediate typically in the synthesis of Panipenem (CAS 87726-17-8) and Darifenacin hydrobromide (CAS 133099-07-7). (R)-(-)-3-Pyrrolidinol Hydrochloride (CAS: 104706-47-0) is a chiral hydroxy derivative of pyrrlodine used in the preparation of chiral niologically active compounds such as muscarinic receptor antagonists and antimicrobial agents. Route of Synthesis of (R)-3-Hydroxypyrrolidine hydrochloride (R)-4-chloro-3-hydroxybutanitrile was reacted with trimethyl chlorosilane in dichloromethane solvent to obtain (R)-4-chloro-3-trimethylsiloxy butanitrile. (R)-4-chloro-3-trimethylsiloxyebutylamine was then hydrogenated on Pd/C catalyst.(R)-3-trimethylsiloxyepyrrolidine was obtained by sodium hydroxide ring closing treatment. Finally, the (R)-3-hydroxypyrrolidine hydrochloride product was obtained by concentrated hydrochloric acid treatment and the trimethylsilyl protective group was removed.Sufficient Capacity: Sufficient facilities and technicians
OEM Package: Custom package and label available
