Chemical Properties:
Package: Bottle, Cardboard Drum, 25kg/Drum, or according to customer's requirement. Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.Commercial Supply Dapoxetine Hydrochloride and Related Intermediates: 3-Chloropropiophenone CAS: 936-59-4 (S)-3-Amino-3-Phenylpropan-1-ol CAS: 82769-76-4 (S)-3-Amino-3-Phenylpropanoic Acid CAS: 40856-44-8 (R)-Diphenylprolinol CAS: 22348-32-9 (S)-Diphenylprolinol CAS: 112068-01-6 (S)-(-)-3-Chloro-1-Phenyl-1-Propanol CAS: 100306-34-1 Dapoxetine Hydrochloride CAS: 129938-20-1| Item | Specifications |
| Appearance | White Crystal |
| Identification | HPLC; IR |
| Purity | ≥99.0% |
| e.e | ≥99.0% |
| Specific Rotation [α]D20 | +66.0°~ +68.0° (C=3, MeOH 25℃) |
| Melting Point | 77.0~81.0℃ |
| Loss on Drying | ≤0.50% |
| Single Impurity | ≤0.50% |
| Total Impurities | ≤1.0% |
| Heavy Metals | ≤20ppm |
| Test Standard | Enterprise Standard |
| Usage | Chiral Compounds; Pharmaceutical Intermediates |
Description:
Specifications:
Package & Storage:
| Chemical Name | (R)-Diphenylprolinol |
| Synonyms | (R)-(+)-α,α-Diphenyl-2-Pyrrolidinemethanol;(R)-(+)-2-(Diphenylhydroxymethyl)pyrrolidine; (R)-(+)- α,α-Diphenylprolinol; (R)-1,1-Diphenylprolinol; (R)-(+)-Diphenyl-2-Pyrrolidinemethanol |
| CAS Number | 22348-32-9 |
| CAT Number | RF-CC114 |
| Stock Status | In Stock, Production Scale Up to Tons |
| Molecular Formula | C17H19NO |
| Molecular Weight | 253.35 |
| Solubility in Chloroform | Almost Transparency |
| Brand | Ruifu Chemical |
Advantages:
FAQ:
Application:
Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of (R)-Diphenylprolinol (CAS: 22348-32-9) with high quality. Shanghai Ruifu Chemical Co., Ltd. plays an important role in the chiral chemistry, the company is committed to the production of chiral compounds. Our products are widely praised by customers. (R)-Diphenylprolinol (CAS 22348-32-9) can be used in the synthesis of Dapoxetine Hydrochloride (CAS 129938-20-1). Dapoxetine Hydrochloride is a short-acting novel selective serotonin reuptake inhibitor marketed for the treatment of premature ejaculation (PE) in men. PE is the most common male sexual disorder. (R)-Diphenylprolinol (CAS 22348-32-9) is the (R)-enantiomer of Diphenylprolinol, a relatively mild norepinephrine-dopamine reuptake inhibitor. (R)-α,α-Diphenylprolinol is more pharmacologically active than its (S)-enatiomer. (R)-Diphenylprolinol can be used for the preparation of the corresponding oxazolidine borane, the compound can be used for borane-mediated asymmetric reduction of ketone.
