Ethyl Isocyanoacetate CAS 2999-46-4 Purity >99.0% (GC)

Chemical Name: Ethyl Isocyanoacetate Synonyms: Isocyanoacetic Acid Ethyl Ester CAS: 2999-46-4 Purity: >99.0% (GC)  Appearance: Light Yellow to Brown Liquid High Quality, Commercial Production E-Mail: alvin@ruifuchem.com

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Package: Fluorinated Bottle, 25kg/Drum, or according to customer's requirement Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moistureShanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of Ethyl Isocyanoacetate (CAS: 2999-46-4) with high quality. We can provide COA, worldwide delivery, small and bulk quantities available. Please contact: alvin@ruifuchem.com
Item Specifications
Appearance Light Yellow to Brown Liquid
Purity / Analysis Method >99.0% (GC)
Refractive Index n20/D 1.4150~1.4230
Total Impurities <1.00%
Infrared Spectrum Conforms to Structure
Proton NMR Spectrum Conforms to Structure
Test Standard Enterprise Standard
Usage Pharmaceutical Intermediates

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Chemical Name Ethyl Isocyanoacetate
Synonyms Isocyanoacetic Acid Ethyl Ester
CAS Number 2999-46-4
CAT Number RF-PI2193
Stock Status In Stock, Production Capacity 300MT/Year 
Molecular Formula C5H7NO2
Molecular Weight 113.11
Boiling Point  194.0~196.0℃(lit.) 
Density   1.035 g/mL at 25℃(lit.) 
Store Under Inert Gas Store Under Inert Gas
Sensitive Light Sensitive, Moisture Sensitive, Heat Sensitive
Solubility  Miscible With Organic Solvents. Slightly Miscible With Water
Brand Ruifu Chemical

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Ethyl Isocyanoacetate (CAS: 2999-46-4) is used as pharmaceutical and organic synthesis intermediates, intermediate of Flumazenil (Anexate). Ethyl Isocyanoacetate is a cyclization synthon used to prepare pyrroles, oxazolines, benzodiazepines, oxazoles and imidazoles. Ethyl isocyanoacetate can be used to prepare pyrroles,1,2 oxazolines, benzodiazepines, oxazoles and imidazoles. Ethyl Isocyanoacetate is a raw material for various APIs and API intermediates, e.g. in the synthesis of Benzodiazepine derivatives , oxazolines, Plinabulin and novel anti-bacterial agents. Applications Novel high crystallinity organic semiconductor; Key starting material for the synthesis of Tankyrase-inhibiting Imidazopyrazinone derivatives; Key raw material for the synthesis of thermal solubility-controlled Phthalocyanine dyes; Key raw material for the synthesis of Imrecoxib, a new selective COX-2 inhibitor for the treatment of osteoarthritis; Raw material in the synthesis of novel Hepatitis C inhibitors.

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