Chemical Properties:
Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement. Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture.Manufacturer Supply, High Purity, Commercial Production Chemical Name: S-Phos CAS: 657408-07-6| Item | Specifications |
| Appearance | White Powder |
| Purity / Analysis Method | >98.0% (HPLC) |
| Solvents | <0.50% |
| NMR | Conforms to Structure |
| Test Standard | Enterprise Standard |
| Usage | Buchwald Ligands & Precatalysts |
Description:
Specifications:
Package & Storage:
| Chemical Name | 2-Dicyclohexylphosphino-2',6'-dimethoxybiphenyl |
| Synonyms | S-Phos; Dicyclohexyl(2',6'-dimethoxy-[1,1'-biphenyl]-2-yl)phosphine |
| CAS Number | 657408-07-6 |
| CAT Number | RF-F27 |
| Stock Status | In Stock |
| Molecular Formula | C26H35O2P |
| Molecular Weight | 410.54 |
| Melting Point | 164.0~166.0℃ |
| Solubility | Soluble in Chloroform |
| Brand | Ruifu Chemical |
Advantages:
FAQ:
Application:
S-Phos (CAS: 657408-07-6) is an air-stable, electron-rich biaryl phosphine ligand developed by the Buchwald group to enhance the reactivity of palladium catalysis during cross-coupling reactions. S-Phos may be used as a ligand in the following processes: Palladium catalyzed Suzuki-Miyaura cross-coupling reaction between Boc-protected aminomethyltrifluoroborate and aryl chlorides or hetaryl chlorides to form the corresponding aminomethylarenes. Palladium catalyzed Suzuki-Miyaura cross-coupling reaction between 4-methyl-substituted piperidinylzinc reagent and different aryl or heteroaryl iodides to form various substituted piperidines. Intramolecular Suzuki-Miyaura coupling to form the 18-membered macrocyclic ring during the multi-step synthesis of riccardin C. Utilized in conjunction with palladium to form a highly active catalyst for C-N bond formation. Ligand/palladium catalyst for general Suzuki-Miyaura cross-coupling reactions. Ligand/palladium catalyst for the Suzuki-Miyaura coupling of aryltrifluoroborates with aryl chlorides. Ligand/palladium catalyst for the Suzuki-Miyaura reaction of heteroaryl halides and heteroaryl boronic acids and esters. Ligand/palladium catalyst for the Kumada-Corriu cross-coupling reaction. Ligand/palladium catalyst for the borylation of aryl halides with pinacol borane. Suzuki couplings involving amino acids. Synthesis of biaryl derivatives of 4-hydroxyphenyl glycine, tyrosine and tryptophan. Synthesis of substituted adamantylzinc reagents using Mg-insertion in the presence of zinc chloride. Highly efficient catalyst for the palladium-catalyzed Suzuki-Miyura reaction of heteroaryl halides and heteroaryl boronic acids and esters.
