Posaconazole Intermediate CAS 170985-85-0 2-[(1S,2S)-1-Ethyl-2-(phenylmethoxy)propyl]hydrazinecarboxaldehyde

Chemical Name: 2-[(1S,2S)-1-Ethyl-2-(phenylmethoxy)propyl]hydrazinecarboxaldehyde CAS: 170985-85-0 Appearance: White or Off-White Powder Purity: ≥98.0% (HPLC) Intermediate of Posaconazole (CAS 171228-49-2)  Contact: Dr. Alvin Huang Mobile/Wechat/WhatsApp: +86-15026746401 E-Mail: alvin@ruifuchem.com

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Chemical Properties:

Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer's requirement. Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.Factory Supply Posaconazole Related Intermediates, Commercial Production Posaconazole CAS 171228-49-2 Posaconazole Intermediate POA CAS 149809-43-8 Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate CAS 184177-81-9 1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine CAS 74853-08-0 2-[(1S,2S)-1-Ethyl-2-(phenylmethoxy)propyl]hydrazinecarboxal CAS 170985-85-0 Diethyl L-(+)-Tartrate CAS 87-91-2
Item Specifications
Appearance White or Off-White Powder
Identification  H-NMR: Conforms to the Standard
Loss on Drying ≤0.50%
Purity / Analysis Method ≥98.0% (HPLC)
Organic Impurities
Any Single Impurity ≤0.50%
Total Organic Impurities ≤2.0%
Heavy Metals ≤20ppm
Test Standard Enterprise Standard
Usage Intermediate of Posaconazole (CAS 171228-49-2) Antifungal Agent

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Chemical Name 2-[(1S,2S)-1-Ethyl-2-(phenylmethoxy)propyl]hydrazinecarboxaldehyde
Synonyms N'-((2S,3S)-2-(Benzyloxy)pentan-3-yl)formohydrazide; N-[[(2S,3S)-2-phenylmethoxypentan-3-yl]amino]formamide; Posaconazole Intermediate; Posaconazole Impurity 33 
CAS Number 170985-85-0
CAT Number RF-PI292
Stock Status In Stock, Production Scale Up to Hundreds of Kilograms
Molecular Formula C13H20N2O2
Molecular Weight 236.31
Shipping Condition Shipped Under Ambient Temperature
Brand Ruifu Chemical

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2-[(1S,2S)-1-Ethyl-2-(Phenylmethoxy)propyl]hydrazinecarboxaldehyde (CAS: 170985-85-0) is an important intermediate of Posaconazole (CAS 171228-49-2). Posaconazole is a triazole antifungal drug widely used in the treatment of invasive infections. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Posaconazole is derived from itraconazole. Its pharmacological effects are similar with azoles, but compared with Itraconazole, it has a stronger inhibitory effect on the C14 demethylation of steroid, especially for Aspergillus. Posaconazole, launched in the UK, is the newest member of the azole class of antifungal agents to reach the market.  

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