Chemical Properties:
Package: Bottle, Aluminum foil bag, 25kg/Cardboard Drum, or according to customer's requirement Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moistureShanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of L-Thyroxine Sodium Hydrate (CAS: 25416-65-3) with high quality. We can provide COA, worldwide delivery, small and bulk quantities available. If you are interested in this product, please send detailed information includes CAS number, product name, quantity to us. Please contact: alvin@ruifuchem.com| Item | Specifications |
| Appearance | Light Yellow to Yellow-Brown Powder |
| Identification Methods | HPLC |
| Purity / Analysis Method | >98.0% (HPLC) |
| Assay (Nonaqueous Titration) | >98.0% |
| Specific Rotation [α]20/D | -6.0° ~ -5.0° (C=3 in Alcohol:1N NaOH 2:1 in Anhydrous) |
| Loss on Drying | <11.00% (60℃,4h) |
| Residue on Ignition | <0.50% |
| Related Substances | |
| Liothyronine | <1.00% |
| Beta hydroxy-T 4a | <0.15% |
| T4-Hydroxy Acetic acid | <0.15% |
| N-Acetyl-T 4 | <0.20% |
| T4-Acetici acid | <0.30% |
| T4-Aldehyde | <0.15% |
| T4-Benzoic Acid | <0.15% |
| Other Single Impurity | <0.15% |
| Total Impurities | <2.00% |
| Infrared Spectrum | Conforms to Structure |
| Test Standard | Enterprise Standard |
| Usage | A Synthetic Hormone for the Research of Hypothyroidism |
Description:
Specifications:
Package & Storage:
| Chemical Name | L-Thyroxine Sodium Hydrate |
| Synonyms | Levothyroxine Sodium Hydrate; L-Thyroxine Sodium Salt Hydrate; L-Thyroxin Monosodium Salt Hydrate; L-Thyroxine·Na; Levothyroxine Sodium; Sodium Levothyroxine; 3,3′,5,5′-Tetraiodo-L-Thyronine Monosodium Salt; 3,3',5,5'-Tetraiodo-L-Thyronine Sodium Salt; Sodium O-(4-Hydroxy-3,5-Diiodophenyl)-3,5-Diiodo-L-Tyrosine |
| CAS Number | 25416-65-3 |
| CAT Number | RF2894 |
| Stock Status | In Stock, Production Scale Up to Tons |
| Molecular Formula | C15H10I4NO4·Na |
| Molecular Weight | 798.85 (Anhydrous Basis) |
| Melting Point | 207℃ |
| Density | 2.381 |
| Stability | Hygroscopic |
| Water Solubility | 0.15 g/L (25℃) |
| Solubility | Very Slightly Soluble in Water, Slightly Soluble in Ethanol (96 percent). It Dissolves in Dilute Solutions of Alkali Hydroxides |
| HS Code | 29379000 |
| Brand | Ruifu Chemical |
Advantages:
How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals. Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc. Advantages? Superior quality, affordable price, professional services and technical support, fast delivery. Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc. Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers. Factory Audit? Factory audit welcome. Please make an appointment in advance. MOQ? No MOQ. Small order is acceptable. Delivery Time? If within stock, three days delivery guaranteed. Transportation? By Express (FedEx, DHL), by Air, by Sea. Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided. Custom Synthesis? Can provide custom synthesis services to best fit your research needs. Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.FAQ:
Stable Supply: Maintain reasonable stock
Professional Service: One stop purchasing service
Technical Support: Technology solution available
Custom Synthesis Service: Ranged from grams to kilos
Fast Delivery: If within stock, three days delivery guaranteed
High Quality: Established a complete quality assurance system
Application:
L-Thyroxine Sodium Hydrate (CAS: 25416-65-3) is a useful research chemical. Its free form Thyroxine (T425600) is one of the thyroid hormones involved in the maintenance of metabolic homeostasis. Synthesized and stored as amino acid residues of thyroglobulin, the major protein component of the thyroid follicular colloid. Synthesis and secretion are regulated by the pituitary hormone (TSH). Deiodinated in peripheral tissues to the active metabolite, liothyronine. The D-form has very little activity as a thyroid hormone, but has been used to treat hyperlipidemia. Levothyroxine is typically used to treat hypothyroidism,and is the treatment of choice for patients with hypothyroidism, who often require lifelong thyroid hormone therapy.It may also be used to treat goiter via its ability to lower thyroid-stimulating hormone (TSH), a hormone that is considered goiter-inducing. Levothyroxine is also used as interventional therapy in patients with nodular thyroid disease or thyroid cancer to suppress thyroid-stimulating hormone (TSH) secretion.Sufficient Capacity: Sufficient facilities and technicians
OEM Package: Custom package and label available