Chemical Properties:
Package: Fluorinated Bottle, 25kg/bag, 25kg/Cardboard Drum, or according to customer's requirement. Stability: Stability Moisture and light sensitive. Incompatible with strong oxidising agents. Storage Condition: Store in sealed containers at cool, dry and ventilated warehouse away from incompatible substances. Protect from light and moisture.Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of L-Leucine (H-Leu-OH; L-Leu; Leu) (CAS: 61-90-5) with high quality, production capacity 5000 Tons per year. As one of the largest amino acids suppliers in China, Ruifu Chemical supplys amino acids up to international standards, such as AJI, USP, EP, JP and FCC standards. We can provide COA, worldwide delivery, small and bulk quantities available. If you are interested in L-Leucine, Please contact: alvin@ruifuchem.com| Safety Statements | 24/25 - Avoid Contact With Skin and Eyes |
| WGK Germany | 3 |
| RTECS | OH2850000 |
| TSCA | Yes |
| HS Code | 2922491990 |
Description:
61-90-5 - Risk and Safety:
Package & Storage:
| Chemical Name | L-Leucine |
| Synonyms | H-Leu-OH; L-Leu; Leu; L-(-)-Leucine; Laevo-Leucine; Leucine; (S)-2-Amino-4-Methylpentanoic Acid; L-2-Amino-4-methylpentanoic acid; alpha-Aminoisocaproic acid; (S)-(+)-Leucine; (S)-Leucine; L-α-Aminoisocaproic Acid; (2S)-2-Amino-4-Methylpentanoic Acid |
| Stock Status | In Stock, Production Capacity 5000 Tons per Year |
| CAS Number | 61-90-5 |
| Molecular Formula | C6H13NO2 |
| Molecular Weight | 131.18 |
| Melting Point | >300℃(lit.) |
| Density | 1.293 g/cm3 |
| Refractive Index | 1.46 |
| Sensitive | Light Sensitive, Moisture Sensitive |
| Water Solubility | 22.4 g/L (20℃) |
| Solubility | Freely Soluble in Formic Acid. Sparing Soluble in Water. Practically Insoluble in Ethanol and in Ether. Dissolves in Dilute Hydrochloric Acid |
| Solubility in Dilute HCl | Almost Transparency |
| Storage Temp. | Sealed in Dry, Store at Room Temperature |
| COA & MSDS | Available |
| Classification | Amino Acids |
| Brand | Ruifu Chemical |
Advantages:
How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals. Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc. Advantages? Superior quality, affordable price, professional services and technical support, fast delivery. Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc. Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers. Factory Audit? Factory audit welcome. Please make an appointment in advance. MOQ? No MOQ. Small order is acceptable. Delivery Time? If within stock, three days delivery guaranteed. Transportation? By Express (FedEx, DHL), by Air, by Sea. Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided. Custom Synthesis? Can provide custom synthesis services to best fit your research needs. Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.FAQ:
Stable Supply: Maintain reasonable stock
Professional Service: One stop purchasing service
Technical Support: Technology solution available
Custom Synthesis Service: Ranged from grams to kilos
Fast Delivery: If within stock, three days delivery guaranteed
High Quality: Established a complete quality assurance system
Sufficient Capacity: Sufficient facilities and technicians
OEM Package: Custom package and label available
Specifications:
| Items | Inspection Standards | Results |
| Appearance | White Crystals or Crystalline Powder | Conforms |
| Identification | Infrared Absorption Spectrum | Conforms |
| Specific Rotation [α]20/D | +14.9° to +16.0°(C=4, 6N HCl) | +15.2° |
| State of Solution (Transmittance) | Clear and Colorless ≥98.0% | 98.5% |
| Chloride (Cl) | ≤0.020% | <0.020% |
| Sulfate (SO4) | ≤0.020% | <0.020% |
| Ammonium (NH4) | ≤0.020% | <0.020% |
| Iron (Fe) | ≤10ppm | <10ppm |
| Heavy Metals (Pb) | ≤10ppm | <10ppm |
| Arsenic (As2O3) | ≤1.0ppm | <1.0ppm |
| Other Amino Acids | Conforms | Conforms |
| Loss on Drying | ≤0.20% | 0.12% |
| Residue on Ignition (Sulfated) | ≤0.10% | 0.06% |
| Assay | 98.5 to 101.0% | 99.7% |
| pH Test | 5.5 to 6.5 (1.0g in 100ml of H2O) | 6.0 |
| Origin | From Non-Animal Source | Conforms |
| Conclusion | Meets AJI97; USP, EP, JP Specifications | |
| Shelf Life | 24 Months From Manufacture Date if Stored Properly | |
| Main Uses | Amino Acids; Food & Feed Additives; Pharmaceutical Intermediates; Nutritional Supplements | |
Application:
L-Leucine (H-Leu-OH; L-Leu; Leu) (CAS: 61-90-5) is used as pharmaceutical raw materials and food additives. L-Leucine is one of the 18 common amino acids, and one of the eight essential amino acids at the human body. It is called branched chain amino acids (BCAA) with L-Isoleucine and L-Valine together because they all contain a methyl side chain in their molecular structure. L-Leucine can be used in the food industry in nutrition supplements, added to food, L-Threonine can improve the nutritional value of protein, so that adequate food nutrients more reasonable. L-Threonine and glucose were hot, fragrant and easy to produce coke chocolate flavor in a flavor enhancer in food processing role. L-Leucine in the feed industry, L-Threonine amino acids can be used as feed additives for the feed supply of protein has opened up new avenues, L-Threonine not only improves the nutritional value of feed, reduce feeding costs. But also get to promote animal growth and development, enhance disease resistance and so many other beneficial effects. 1. L-leucine can promote insuli secretion and lower blood sugar. 2. It promotes sleep, reduces sensitivity to pain, relieves migraine, relieves anxiety and tension, relieves the symptoms of chemical reaction disorder caused by alcohol, and helps control alcoholism; 3. Leucine supplements are often recommended for patients after surgery because it can help treat dizziness and promote healing of skin wounds and bone heads. 4. Amino acid infusion and comprehensive amino acid preparation are often prepared for treatment or health care;Also can be used as food, cosmetics and feed additives. Plant growth promoters. 5. Amino acid drugs. Used as amino acid infusion and comprehensive amino acid preparations. For the diagnosis and treatment of children with idiopathic high blood sugar and glucose metabolism disorders,bile liver disease associated with reduced secretion , anemia, poisoning, muscular dystrophy, poliomyelitis, neuritis and mental illness. Diabetes, cerebral vascular sclerosis and kidney disease associated with proteinuria and hematuria is contraindicated. Gastric and duodenal ulcer patients should not be served. 6. The product is used as a nutritional supplement,an amino acid infusion preparation and a comprehensive amino acid preparation,a hypoglycemic agent, a plant growth promoter.The product can be used as a spice according to GB 2760-8 .61-90-5 AJI97 Test Method:
L-Leucine (H-Leu-OH; L-Leu; Leu) (CAS: 61-90-5) AJI 97 Test Method Identification: Compare the infrared absorption spectrum of the sample with that of the standard by potassium bromide disc method. Specific Rotation [α]20/D: Dried Sample, C=4, 6mol/L HCl State of Solution (Transmittance): 0.5g in 10ml of 1mol/L, HCl spectrophotometer, 430nm, 10nm cell thickness. Chloride (Cl): 0.7g, A-1, ref: 0.40ml of 0.01mol/L HCl Ammonium (NH4): B-2 Sulfate (SO4): 1.2g, (1), ref: 0.50ml of 0.005mol/L H2SO4 Iron (Fe): 1.5g, (1), ref: 1.5ml of Iron Std. (0.01mg/ml) Heavy Metals (Pb): 2.0g, (4), ref: 2.0ml of Pb Std. (0.01mg/ml) Arsenic (As2O3): 2.0g, (1), ref: 2.0ml of As2O3 Std. Other Amino Acids: Test Sample: 50μg, B-6-a, control: L-Leu 0.25μg Loss on Drying: at 105℃ for 3 hours. Assay: Dried sample, 130mg, (3), 3ml of formic acid, 50ml of glacial acetic acid, 0.1mol/L HCLO4 1ml=13.117mg C6H13NO2 pH Test: 1.0g in 100ml of H2O