Chemical Properties:
Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moistureShanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of 3α-Hydroxy-7-oxo-5β-Cholanic Acid (CAS: 4651-67-6) with high quality, commercial production. We can provide COA, worldwide delivery, small and bulk quantities available. Please contact: alvin@ruifuchem.com| Item | Specifications |
| Appearance | White to Off-White Crystalline Powder or Powder; No Foreign Substance, No Obvious Odor |
| Purity / Analysis Method | >99.5% (HPLC) |
| Melting Point | 201.0~205.0℃ |
| Loss on Drying | <0.50% |
| Residue on Ignition | <0.20% |
| Related Substances | |
| Single Impurity | <0.50% |
| Total Impurities | <0.50% |
| Heavy Metals | ≤10ppm |
| Proton NMR Spectrum | Conforms to Structure |
| Test Standard | Enterprise Standard |
| Usage | Intermediate of Obeticholic Acid (CAS: 459789-99-2) |
Description:
Specifications:
Package & Storage:
| Chemical Name | 3α-Hydroxy-7-oxo-5β-Cholanic Acid |
| Synonyms | 3α-Hydroxy-7-keto-5β-Cholanic Acid; 3alpha-Hydroxy-7-oxo-5beta-Cholanic Acid; 7-Ketolithocholic Acid; Ursodeoxycholic Acid EP Impurity F |
| CAS Number | 4651-67-6 |
| CAT Number | RF-PI1988 |
| Stock Status | In Stock, Production Scale Up to Tons |
| Molecular Formula | C24H38O4 |
| Molecular Weight | 390.56 |
| Density | 1.124±0.060 g/cm3 |
| Brand | Ruifu Chemical |
Advantages:
FAQ:
Application:
3α-Hydroxy-7-oxo-5β-Cholanic Acid (CAS: 4651-67-6) is an intermediate of Obeticholic Acid (CAS: 459789-99-2). Obeticholic Acid is also called 6-Ethylchenodeoxycholic acid. Obeticholic Acid is a new derivative of chenodeoxycholic acid (CDCA) in human primary bile acids, a natural ligand for farnesoid x receptors (FXR). Obeticholic Acid was developed by American pharmaceutical company Intercept as the first drug to treat cholestatic liver disease in 20 years, and it is administered on patients that do not respond well to or cannot tolerate the old standard treatment drug ursodeoxycholic acid. Obeticholic Acid has also been tested to treat a more common form of fatty liver – non-alcoholic fatty liver disease (NAFLD). Obeticholic Acid can also be developed to treat other liver and intestine diseases.
