Chemical Properties:
Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer's requirement. Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.Manufacturer with High Purity and Stable Quality Chemical Name: Cisatracurium Besylate CAS: 96946-42-8 API High Quality, Commercial Production| Item | Specifications |
| Appearance | White or Almost White Powder, Odorless, Slightly Hygroscopic |
| Solubility | Freely soluble in dichloromethane, acetonitrile, slight soluble in water |
| Specific Rotation | -35.0° to -45.0° (C=10mg/ml, 0.1mg/ml benzene sulfonic acid) |
| Identification | Dissolve with dilute hydrochoric acid, dropwise dilute bismuth potassium iodide TS, yellow precipitations will be produced |
| Identification | 1. HPLC ; 2. I.R |
| Assay | 95.0~102.0% (C65H82N2O18S2 on the dried basis) |
| pH | 3.5 to 5.0 |
| Clarity & Color of the Solution | Should be Clear & Colorless |
| Loss on Drying | ≤2.0% |
| Residual on Ignition | ≤0.20% |
| Heavy Metals | ≤20ppm |
| Trans-Trans Isomer | ≤0.50% |
| Cis-Trans Isomer | ≤0.50% |
| Mono-quaternaries | ≤1.50% |
| Anyother Individual Impurity | ≤1.50% |
| Total Impurities | ≤5.0% |
| Optical Isomer SS-Isomer | ≤1.50% |
| Optical Isomer RS- Isomer | ≤1.00% |
| Sulfate | ≤50ppm |
| Ethyl | ≤0.50% |
| Acetone | ≤0.50% |
| Methanol | ≤0.3% |
| Dichloromethane | ≤0.06% |
| Acetonitrile | ≤0.041% |
| Methylbenzene | ≤0.089% |
| Residual Solvents Acetonitrile | ≤410ppm |
| Test Standard | Chinese Pharmacopoeia (CP) |
| Usage | Active Pharmaceutical Ingredient (API) |
Description:
Specifications:
Package & Storage:
| Chemical Name | Cisatracurium Besylate |
| CAS Number | 96946-42-8 |
| CAT Number | RF-API13 |
| Stock Status | In Stock, Production Scale Up to Tons |
| Molecular Formula | C53H72N2O12.2C6H5O3S |
| Molecular Weight | 1243.49 |
| Melting Point | 90.0~93.0℃ |
| Shipping Condition | Under Ambient Temperature |
| Brand | Ruifu Chemical |
Advantages:
FAQ:
Application:
Cisatracurium Besylate (CAS 96946-42-8) is the benzene sulfonate salt form of atracurium. It is a kind of artificially synthetic non-depolarizing muscle relaxants with its role similar as tubocurarine. The treatment dose does not affect the heart, liver and kidney function. It also has no accumulation property. It also can induce the release of histamine when used at large doses. For muscle relaxation or breathing control required in surgery, compared with current clinical major muscle-relaxing anesthetic drugs, cisatracurium besylate is not metabolized through liver or kidney, and has cardiovascular stability; its effect of muscle relaxation is 3 times as strong as atracurium without any cardiovascular side effects. Cisatracurium besylate is mainly applied to general anesthesia, and can be widely used in intubation, treating liver and kidney dysfunction, used in cardiovascular surgery and elderly and pediatric patients. Compared with atracurium, this product has no dose-dependent adverse effects of histamine release; however, the disadvantage is that patients with liver and kidney dysfunction should administrate with caution. Since 1996 for the first time when this drug has entered into market in UK, foreign countries have gradually applied it to replace vecuronium and atracurium as the mainstream of clinical muscle relaxants.
