3-[1-(Dimethylamino)ethyl]phenol CAS 105601-04-5 Rivastigmine Tartrate Intermediate Purity >98.0% (HPLC)

Chemical Name: 3-[1-(Dimethylamino)ethyl]phenol  CAS: 105601-04-5 Purity: >98.0% (HPLC) Appearance: Off-White to Light Yellow Solid Intermediate of Rivastigmine Tartrate (CAS: 129101-54-8)  Contact: Dr. Alvin Huang Mobile/Wechat/WhatsApp: +86-15026746401 E-Mail: alvin@ruifuchem.com

Products Details

Chemical Properties:

Package: Fluorinated Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement. Storage Condition: Keep the container tightly closed and store in a cool, dry and well-ventilated warehouse away from incompatible substances. Protect from light and moisture. Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery. Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of 3-[1-(Dimethylamino)ethyl]phenol (CAS: 105601-04-5) with high quality, intermediate of Rivastigmine Tartrate (CAS: 129101-54-8). Ruifu Chemical can provide worldwide delivery, competitive price, excellent service, small and bulk quantities available. Purchase 3-[1-(Dimethylamino)ethyl]phenol, Please contact: alvin@ruifuchem.com

Description:

Package/Storage/Shipping:

Chemical Name 3-[1-(Dimethylamino)ethyl]phenol   
Synonyms N,N-Dimethyl-N-[1-(3’-Hydroxyphenyl)ethyl]amine; Rivastigmine Tartrate Intermediate 2
Stock Status In Stock, Commercial Production  
CAS Number 105601-04-5 
Molecular Formula C10H15NO
Molecular Weight 165.24 g/mol
Melting Point 87.0~89.0℃ 
Boiling Point 240.0~244.0℃ at 760 mmHg
Density 1.021 
Sensitive Air Sensitive 
Solubility  Soluble in Methanol
COA & MSDS Available
Origin Shanghai, China
Category   Intermediate of Rivastigmine Tartrate (CAS: 129101-54-8) 
Brand Ruifu Chemical

Advantages:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com  15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals. Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc. Advantages? Superior quality, affordable price, professional services and technical support, fast delivery. Quality AssuranceStrict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc. SamplesMost products provide free samples for quality evaluation, shipping cost should be paid by customers. Factory AuditFactory audit welcome. Please make an appointment in advance. MOQ? No MOQ. Small order is acceptable. Delivery Time? If within stock, three days delivery guaranteed. TransportationBy Express (FedEx, DHL), by Air, by Sea. Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided. Custom SynthesisCan provide custom synthesis services to best fit your research needs. Payment TermsProforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

FAQ:

Stable Supply: Maintain reasonable stock    

Professional Service: One stop purchasing service

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

Fast Delivery: If within stock, three days delivery guaranteed

High Quality: Established a complete quality assurance system

Sufficient Capacity: Sufficient facilities and technicians

OEM Package: Custom package and label available

Specifications:

Items Inspection Standards Results
Appearance Off-White to Light Yellow Solid  Complies      
Purity / Analysis Method >98.0% (HPLC)  98.3% 
Infrared Spectrum Consistent with Structure Complies 
1H NMR Spectrum Consistent with Structure Complies
Conclusion The product has been tested and complies with the given specifications

105601-04-5 - Safety Information:

105601-04-5 - Application:

Hazard Symbols T - Toxic Risk Codes R25 - Toxic if swallowed R41 - Risk of serious damage to eyes Safety Description S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S39 - Wear eye / face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) HS Code 29222900903-[1-(Dimethylamino)ethyl]phenol (CAS: 105601-04-5) is an intermediate of Rivastigmine Tartrate (CAS: 129101-54-8). Rivastigmine Tartrate is rivastigmine Alzheimer's disease drugs, rivastigmine is physostigmine derivative by Novartis for the first time successfully developed the trade name Exelon, a molecule with there carbamate structure, is a kind of amino acid of selective cerebral cholinesterase inhibitor, can also inhibit the acetylcholinesterase and butyrylcholinesterase, cholinergic neurons by delaying the release of acetylcholine degradation and energy promoting cholinergic nerve conduction, can improve cognitive function disorders mediated by cholinergic, thereby improving the cognitive function of Alzheimer's disease patients. Rivastigmine plasma protein binding is weak, easily through the blood-brain barrier, which has a high degree of brain selectivity. It not only selectively acts on the most easily affected cerebral cortex and hippocampus, but also preferentially inhibits the dominant subtype of AChE in the brain, resulting in a reduction in the efficacy of peripheral cholinergic side effects. Rivastigmine in vivo half-life is short and long duration of action. Unlike tacrine, this product in the hippocampus and cortex of G1 enzyme inhibitory effect is stronger. Clinic for the treatment of mild to moderate Alzheimer-type dementia, or Alzheimer's disease can be suspected Alzheimer's disease clinically.

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