Chemical Properties:
Package: Fluorinated Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement. Storage Condition: Store in sealed containers at cool and dry (2~8℃) warehouse away from incompatible substances. Protect from light and moisture.Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of Nε-Cbz-L-Lysine (H-Lys(Z)-OH) (CAS: 1155-64-2) with high quality. Ruifu Chemical supplys a series of amino acids and derivatives. We can provide worldwide delivery, small and bulk quantities available. Purchase H-Lys(Z)-OH, Please contact: alvin@ruifuchem.com| Safety Statements | 24/25 - Avoid contact with skin and eyes. | Hazard Class | IRRITANT |
| WGK Germany | 3 | HS Code | 2922491990 |
Description:
Safety Information:
Package & Storage:
| Chemical Name | Nε-Cbz-L-Lysine |
| Synonyms | H-Lys(Z)-OH; N(epsilon)-Cbz-L-Lysine; Nε-Carbobenzoxy-L-Lysine; N(epsilon)-Carbobenzoxy-L-Lysine; Nε-Benzyloxycarbonyl-L-Lysine; N(epsilon)-Benzyloxycarbonyl-L-Lysine; N6-Cbz-L-Lysine; Lysine(Z)-OH |
| Stock Status | In Stock |
| CAS Number | 1155-64-2 |
| Molecular Formula | C14H20N2O4 |
| Molecular Weight | 280.32 g/mol |
| Melting Point | 230.0~260.0℃ |
| Density | 1.1816 |
| Solubility in Hot HCl | Almost Transparency |
| Storage Temp. | Cool & Dry Place (2~8℃) |
| COA & MSDS | Available |
| Category | Amino Acids and Derivatives |
| Brand | Ruifu Chemical |
Advantages:
How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals. Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc. Advantages? Superior quality, affordable price, professional services and technical support, fast delivery. Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc. Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers. Factory Audit? Factory audit welcome. Please make an appointment in advance. MOQ? No MOQ. Small order is acceptable. Delivery Time? If within stock, three days delivery guaranteed. Transportation? By Express (FedEx, DHL), by Air, by Sea. Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided. Custom Synthesis? Can provide custom synthesis services to best fit your research needs. Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.FAQ:
Stable Supply: Maintain reasonable stock
Professional Service: One stop purchasing service
Technical Support: Technology solution available
Custom Synthesis Service: Ranged from grams to kilos
Fast Delivery: If within stock, three days delivery guaranteed
High Quality: Established a complete quality assurance system
Sufficient Capacity: Sufficient facilities and technicians
OEM Package: Custom package and label available
Specifications:
| Items | Inspection Standards | Results |
| Appearance | White Powder | White Powder |
| Specific Rotation [α]20/D | +14.0°±2.0° (C=0.5 1N HCl) | +15.4° |
| Melting Point | 230.0~260.0℃ | 232.0~233.5℃ |
| Loss on Drying | <1.00% (80℃, 2h) | 0.41% |
| H-Lys(Z)-OH Purity | >98.0% (HPLC) | 99.14% |
| Clarity of Solution | 0.3 gram in 2ml TFA Clear Solution | Complies |
| NMR Spectrum 1H | Conforms to Structure | Complies |
| Infrared Spectrum | Conforms to Structure | Complies |
| Conclusion | The product has been tested & complies with the given specifications | |
Application:
Nε-Cbz-L-Lysine (H-Lys(Z)-OH) (CAS: 1155-64-2) is an amino acid derivative and an intermediate in chiral organic synthesis. Its main purpose is to participate as a molecular skeleton in the synthesis of chiral drug molecules and biologically active molecules. In addition, the carboxyl group in Nε-Cbz-L-Lysine can undergo esterification in the presence of an amino group. The ester group protected by benzyl in the molecular structure can be easily removed under acidic conditions, releasing free carboxyl groups. Synthesis route For the synthesis of Nε-Cbz-L-Lysine, the conventional synthesis method is from the lysine of its corresponding configuration and the acid chloride of another fragment Starting from the reaction of the amino group and the acid chloride to generate the corresponding amide to obtain the target product Nε-Cbz-L-Lysine. This route requires the addition of alkali as an acid binding agent, such as sodium hydroxide. Environmental hazards as an organic amine, Nε-Cbz-L-Lysine is harmful to the water environment and cannot allow undiluted or large amounts of products to contact groundwater, waterways or sewage systems.Method of Analysis:
Column: 4.6*250mm, Sinochrom ODS-BP 5μm Solvent A: 0.1% trifluoroacetic in 100% water Solvent B: 0.1% trifluoroacetic in 100% acetonitrile Gradient A B 0.01min 90% 10% 20.0min 0% 100% 25.0min stop Flow rate: 1.0ml/min Wavelength: 220nm Sample Description: 3mg/ml ACN:H2O=1:1 Volume: 15μl