Chemical Properties:
Package: Fluorinated Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement. Storage Condition: Store in sealed containers at cool and dry (2~8℃) warehouse away from incompatible substances. Protect from light and moisture.Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of Glycine tert-Butyl Ester Hydrochloride (H-Gly-OtBu·HCl) (CAS: 27532-96-3) with high quality. Ruifu Chemical supplys a series of amino acids and derivatives. We can provide worldwide delivery, small and bulk quantities available. Purchase H-Gly-OtBu·HCl, Please contact: alvin@ruifuchem.comDescription:
Package & Storage:
| Chemical Name | Glycine tert-Butyl Ester Hydrochloride |
| Synonyms | H-Gly-OtBu·HCl; Gly-OtBu·HCl; Glycine t-Butyl Ester Hydrochloride; Glycine tert-Butyl Ester HCl; tert-Butyl Glycinate Hydrochloride |
| Stock Status | In Stock, Production Capacity 35 Tons per Month |
| CAS Number | 27532-96-3 |
| Molecular Formula | C6H13NO2·HCl |
| Molecular Weight | 167.63 g/mol |
| Melting Point | 141.0~143.0℃(lit.) |
| Sensitive | Hygroscopic |
| Solubility | Soluble in Methanol and Water |
| Storage Temp. | Cool & Dry Place (2~8℃) |
| COA & MSDS | Available |
| Category | Amino Acids and Derivatives |
| Brand | Ruifu Chemical |
Advantages:
How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals. Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc. Advantages? Superior quality, affordable price, professional services and technical support, fast delivery. Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc. Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers. Factory Audit? Factory audit welcome. Please make an appointment in advance. MOQ? No MOQ. Small order is acceptable. Delivery Time? If within stock, three days delivery guaranteed. Transportation? By Express (FedEx, DHL), by Air, by Sea. Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided. Custom Synthesis? Can provide custom synthesis services to best fit your research needs. Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.FAQ:
Stable Supply: Maintain reasonable stock
Professional Service: One stop purchasing service
Technical Support: Technology solution available
Custom Synthesis Service: Ranged from grams to kilos
Fast Delivery: If within stock, three days delivery guaranteed
High Quality: Established a complete quality assurance system
Sufficient Capacity: Sufficient facilities and technicians
OEM Package: Custom package and label available
Specifications:
| Items | Inspection Standards | Results |
| Appearance | White Crystalline Powder | Complies |
| Melting Point | 141.0~143.0℃ | 141.0~142.0℃ |
| Loss on Drying | <0.50% | 0.36% |
| Heavy Metals (Pb) | ≤10ppm | <10ppm |
| Glycine (Gly) | ≤0.10% (TLC) | <0.10% |
| H-Gly-OtBu·HCl Assay | 98.0~102.0% (Titration by AgNO3) | 99.36% |
| Infrared Spectrum | Conforms to Structure | Complies |
| Proton NMR Spectrum | Conforms to Structure | Complies |
| Solubility in H2O 50mg/ml (5%) | Colorless, Clear to Very Slightly Hazy | Pass |
| Conclusion | The product has been tested & complies with the given specifications | |
27532-96-3 - Risk and Safety:
Application:
Risk Codes 36/37/38 - Irritating to eyes, respiratory system and skin. Safety Description 24/25 - Avoid contact with skin and eyes. WGK Germany 3 FLUKA BRAND F CODES 10-23 TSCA No HS Code 2922491990Glycine tert-Butyl Ester Hydrochloride (H-Gly-OtBu·HCl) (CAS: 27532-96-3) is not only an important chemical raw material, but also widely used in drug synthesis and has good development prospects. Amino acids and derivatives, used in peptide synthesis, organic synthesis intermediates, pharmaceutical intermediates, biochemical reagents, chemical reagents. Preparation 1400L t-Butyl Acetate, 105KG Glycine and 180KG Perchloric Acid were added dropwise at a uniform speed in a 2000L reaction tank. React at 0-10℃ for about 48-72 hours. TLC monitors the reaction during the reaction. After the glycine reaction is more than 90%, use 4 N sodium hydroxide aqueous solution to adjust the PH 6.5-7.5 to separate the organic layer. The water layer continues to be extracted with tert-Butyl Acetate. After the water product is basically extracted to the 95%, all product layers are combined, washed with brine to TLC purity to obtain 1500L tert-Butyl Glycine/tert-Butyl Ethyl Ester solution, concentrate and recover tert-Butyl Ethyl Ester to obtain 180KG of tert-Butyl Glycine, add 100L of Ethyl Ethyl Ester, pass hydrogen chloride to PH0.5, stir and cool the cold crystal, and centrifugally wash to obtain 182KG of tert-Butyl Glycine Hydrochloride.