Chemical Properties:
Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer's requirement. Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.Manufacturer with High Purity and Stable Quality Chemical Name: Guanfacine Hydrochloride Synonyms: Guanfacine HCl CAS: 29110-48-3 Guanfacine Hydrochloride is a selective α2A-adrenoceptor agonist. Antihypertensive API High Quality, Commercial Production| Item | Specifications |
| Appearance | White to Off-White Crystalline Powder |
| Identification | Infrared Absorption; HPLC |
| Loss on Drying | ≤0.50% |
| Residue on Ignition | ≤0.10% |
| Heavy Metals | ≤20ppm |
| Assay | 98.0%~102.0% (HPLC on dried basis) |
| Chromatographic Purity | ≥99.0% |
| Test Standard | USP Standard |
| Usage | Active Pharmaceutical Ingredient (API) |
Description:
Specifications:
Package & Storage:
| Chemical Name | Guanfacine Hydrochloride |
| Synonyms | Guanfacine HCl |
| CAS Number | 29110-48-3 |
| CAT Number | RF-API40 |
| Stock Status | In Stock, Production Scale Up to Tons |
| Molecular Formula | C9H10Cl3N3O |
| Molecular Weight | 282.55 |
| Melting Point | 211.0~215.0℃ |
| Brand | Ruifu Chemical |
Advantages:
FAQ:
Application:
Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of Guanfacine Hydrochloride (CAS: 29110-48-3) with high quality. Guanfacine hydrochloride centrally acting a-adrenoceptor agonist. Antihypertensive. Guanfacine hydrochloride, an anti-hypertensive agent, is a selective α2A-adrenoceptor agonist with Kd of 31 nM and displays 60-fold selectivity over α2B-adrenoceptors. Guanfacine lowers both systolic and diastolic blood pressure by activating the central nervous system α2A norepinephrine autoreceptors, which results in reduced peripheral sympathetic outflow and thus a reduction in peripheral sympathetic tone. The therapeutic applications for guanfacine are similar to those of the other centrally acting α2-adrenergic agonists and methyldopa. It has been effective as monotherapy in the treatment of patients with mild to moderate hypertension.
