Chemical Properties:
Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer's requirement. Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.Manufacturer Commercial Supply Remdesivir and Related Intermediates with High Quality Remdesivir CAS 1809249-37-3 2-Ethyl-1-butanol CAS 97-95-0 Trimethylsilyl Cyanide CAS 7677-24-9 4-Nitrophenol CAS 100-02-7 2-Ethylbutyl ((S)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate CAS 1911578-98-7 N-[(S)-(4-nitrophenoxy)phenoxyphosphinyl]-L-Alanine 2-ethylbutyl ester CAS 1354823-36-1 (S)-2-Ethylbutyl 2-Aminopropanoate Hydrochloride CAS 946511-97-3 Remdesivir Metabolite (GS-441524) CAS 1191237-69-0 Remdesivir N-2 Intermediate CAS 1191237-80-5 2,3,5-Tri-O-benzyl-D-ribonolactone CAS 55094-52-5 7-Bromopyrrolo[2,1-f][1,2,4]triazin-4-amine CAS 937046-98-5 Pyrrolo[1,2-F][1,2,4]Triazin-4-Amine CAS 159326-68-8 4-Amino-7-iodopyrrolo[2,1-f][1,2,4]triazine CAS 1770840-43-1| Item | Specifications |
| Appearance | White to Off-White Powder |
| Infrared Spectrum | Conforms to Structure |
| Purity | ≥99.0% |
| Loss on Drying | ≤0.50% |
| Single Impurity | ≤0.50% |
| Total Impurities | ≤1.0% |
| Heavy Metals | ≤20ppm |
| Test Standard | Enterprise Standard |
| Usage | Intermediate of Remdesivir (CAS 1809249-37-3) |
Description:
Specifications:
Package & Storage:
| Chemical Name | 2-Ethylbutyl ((S)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate |
| Synonyms | N-[(S)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-L-Alanine 2-ethylbutyl ester; Remdesivir Intermediate; Remdesivir-001; Remdesivir Impurity 21 |
| CAS Number | 1911578-98-7 |
| CAT Number | RF-PI303 |
| Stock Status | In Stock, Production Scale Up to Hundreds of Kilograms |
| Molecular Formula | C21H27N2O7P |
| Molecular Weight | 495.38 |
| Density | 1.2g/cm3 |
| Melting Point | 92.0~96.0℃(lit.) |
| Boiling Point | 356.7℃ at 760 mmHg |
| Shipping Condition | Shipped Under Ambient Temperature |
| Brand | Ruifu Chemical |
Advantages:
FAQ:
Application:
2-Ethylbutyl ((S)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate (CAS 1911578-98-7) is an advanced key intermediate in the preparation of Remdesivir related analogs. Remdesivir is a monophosphoramidate prodrug of an adenosine analog, is an investigational broad-spectrum antiviral agent with in vitro activity against SARS coronavirus, MERS coronavirus and, more recently, Covid-19. Remdesivir was mainly developed as a treatment for filovirus infections such as Ebola virus disease or Marburg virus. Subsequently, Remdesivir was found to show antiviral activity against other single-stranded RNA viruses such as respiratory syncytial virus, Nipah virus, Hendra virus, Junin virus, Lassa fever virus and the coronaviruses (including MERS and SARS viruses). Recently it is being studied as a promising medication for the treatment of COVID-19 (new SARS type virus). Remdesivir, developed by Gilead Sciences, is an adenosine prodrug that metabolizes into its active form GS-441524 which interferes with the action of viral RNA-dependent RNA polymerase and evades proofreading by viral exoribonuclease (ExoN), causing a decrease in viral RNA production.
