Chemical Properties:
Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement. Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture.Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of 6-Chlorooxindole (CAS: 56341-37-8) with high quality, commercial production. Welcomed to order.| Item | Specifications |
| Appearance | Off-White to Light Brown Crystalline Powder |
| 1 H NMR Spectrum | Consistent With Structure |
| LCMS | Consistent With Structure |
| Purity (LCMS) | >99.0% |
| Melting Point | 195.0~199.0℃ |
| Loss on Drying | <1.00% |
| Total Impurities | <1.00% |
| Test Standard | Enterprise Standard |
| Usage | Intermediate of Ziprasidone Hydrochloride (CAS: 138982-67-9) |
Description:
Specifications:
Package & Storage:
| Chemical Name | 6-Chlorooxindole |
| Synonyms | 6-Chloro-2-Oxoindole; 6-Chloro-2-Indolinone; 6-Chloro-1,3-Dihydro-indole 2-one; 6-Chloro-1,3-Dihydroindole-2-one |
| CAS Number | 56341-37-8 |
| CAT Number | RF-PI1611 |
| Stock Status | In Stock, Production Scale Up to Tons |
| Molecular Formula | C8H6ClNO |
| Molecular Weight | 167.59 |
| Density | 1.362±0.06 g/cm3 |
| Brand | Ruifu Chemical |
Advantages:
FAQ:
Application:
6-Chlorooxindole (CAS: 56341-37-8) is an intermediate of Ziprasidone Hydrochloride (CAS: 138982-67-9). Ziprasidone Hydrochloride is the hydrochloride salt of a benzisothiazolylpiperazine analog structurally related to the atypical antipsychotic drug tiospirone that antagonizes both central serotonin 5-HT2A (Ki = 0.42 nM) and dopamine D2 (Ki = 4.8 nM) receptors. It is also a potent agonist at 5-HT1A receptors (Ki = 3.4 nM), increasing cortical dopamine release which may offset negative effects associated with dopamine D2 antagonism, and an inverse agonist at 5-HT1B and 5-HT1D receptors (pKis = 8.8 and 8.6, respectively).
