Chemical Properties:
Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moistureRuifu Chemical Supply Almotriptan Malate Intermediates: Almotriptan Malate CAS 181183-52-8 1-((4-Hydrazinylbenzyl)sulfonyl)pyrrolidine Hydrochloride CAS 334981-11-2 4-[(1-Pyrrolidinylsulfonyl)methyl]aniline CAS 334981-10-1 1-[(4-Nitrophenylmethyl)sulfonyl]pyrrolidine CAS 340041-91-0 4-Chlorobutyraldehyde Diethyl Acetal CAS 6139-83-9| Item | Specifications |
| Purity / Analysis Method | >98.0% (HPLC) |
| Loss on Drying | <1.00% |
| Test Standard | Enterprise Standard |
| Usage | Intermediate of Almotriptan Malate (CAS: 181183-52-8) |
Description:
Specifications:
Package & Storage:
| Chemical Name | 1-[(4-Nitrophenylmethyl)sulfonyl]pyrrolidine |
| Synonyms | N-[(4-Nitrophenyl)-methylsulfonyl]pyryolidine; 1-((4-Nitrobenzyl)sulfonyl)pyrrolidine |
| CAS Number | 340041-91-0 |
| CAT Number | RF-PI1959 |
| Stock Status | In Stock, Production Scale Up to Tons |
| Molecular Formula | C11H14N2O4S |
| Molecular Weight | 270.30 |
| Brand | Ruifu Chemical |
Advantages:
FAQ:
Application:
1-[(4-Nitrophenylmethyl)sulfonyl]pyrrolidine (CAS: 340041-91-0) is an intermediate in the Preparation of Almotriptan Malate (CAS: 181183-52-8). Almotriptan Malate is an agonist of the serotonin (5-HT) receptor subtypes 5-HT1B and 5-HT1D (IC50s=12 and 13 nM, respectively, in a radioligand binding assay). Almotriptan Malate (LAS 31416) is a selective 5-hydroxytryptamine1B/1D (5-HT1B/1D) receptor agonist, used for the treatment of Migraine attacks in adults. Almotriptan, marketed in 2000, has the highest oralbioavailability among all triptans. It is metabolizedby both MAO-A and CYP3A4, thus has a more favorableside effects profile when compared with Sumatriptan.
