Indacaterol Maleate Intermediate CAS 312753-53-0 5,6-Diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride High Purity

5,6-Diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride  CAS: 312753-53-0 Appearance: White to Off-White Powder Purity: ≥98.0% (HPLC)  Intermediate of Indacaterol Maleate (CAS: 753498-25-8) in the treatment of COPD  Inquiry: alvin@ruifuchem.com

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Chemical Properties:

Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer's requirement. Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.Commercial Supply Indacaterol Maleate (CAS: 753498-25-8) Related Intermediates: 5,6-Diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride CAS: 312753-53-0 8-Benzyloxy-5-(2-Bromoacetyl)-2-Hydroxyquinoline CAS: 100331-89-3 5-(2R)-2-Oxiranyl-8-benzyloxy-2(1H)-quinolinone CAS: 173140-90-4
Item Specifications
Appearance White to Off-White Powder
Purity / Analysis Method ≥98.0% (HPLC)
Loss on drying ≤0.50%
Individual Impurity ≤0.50%
Total Impurities ≤1.0%
Residue on Ignition ≤0.50%
Test Standard Enterprise Standard
Usage Indacaterol Maleate (CAS: 753498-25-8) Intermediate

Description:

Specifications:

Package & Storage:

Chemical Name 5,6-Diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride  
Synonyms Indacaterol Maleate Intermediate
CAS Number 312753-53-0
CAT Number RF-PI125
Stock Status In Stock, Production Scale Up to Hundreds of Kilograms
Molecular Formula C13H20ClN
Molecular Weight 225.76
Brand Ruifu Chemical

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Application:

Indacaterol Maleate (CAS: 753498-25-8) is a new, ultra-long-acting, rapid onset β(2)-adrenoceptor agonist and bronchodilator. It is used in the treatment of chronic obstructive pulmonary disease (COPD) and asthma. The European Medicines Agency (EMA) approved indacaterol as a drug in 2009 under the Onbrez trade name while in the United States the Food and Drug Administration approved it under the trade name Arcapta in 2011. The drug is manufactured as its maleate salt form. Also, indacaterol is a chiral molecule; however, only the pure R-enantiomer is distributed. It needs to be taken only once a day, unlike competitors formoterol and salmeterol.  

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