5-Fluoro-2-Oxindole CAS 56341-41-4 Purity >99.0% (LCMS) Sunitinib Malate Intermediate Factory

Chemical Name: 5-Fluoro-2-Oxindole  CAS: 56341-41-4 Purity: >99.0% (LCMS) Appearance: Light Yellow Crystalline Powder Intermediate of Sunitinib Malate (CAS: 341031-54-7) High Quality, Commercial Production E-Mail: alvin@ruifuchem.com

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Chemical Properties:

Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement. Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture.Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of 5-Fluoro-2-Oxindole (CAS: 56341-41-4) with high quality, commercial production. Welcomed to order.
Item Specifications
Appearance Light Yellow Crystalline Powder
1 H NMR Spectrum Consistent With Structure
LCMS Consistent With Structure
Purity / Analysis Method >99.0% (LCMS)
Melting Point 143.0~147.0℃
Loss on Drying <0.50%
Total Impurities <1.00%
Test Standard Enterprise Standard
Usage Pharmaceutical Intermediates; Sunitinib Malate Intermediate

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Chemical Name 5-Fluoro-2-Oxindole
Synonyms 5-Fluorooxindole; 5-Fluoro-2-indolinone; 5-Fluoroindolin-2-one; 5-Fluoro-1,3-Dihydro-indol-2-one
CAS Number 56341-41-4
CAT Number RF-PI1543
Stock Status In Stock, Production Scale Up to Tons
Molecular Formula C8H6FNO
Molecular Weight 151.14
Density   1.311±0.06 g/cm3
Brand Ruifu Chemical

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Application:

5-Fluoro-2-Oxindole (CAS: 56341-41-4) is mainly used in pharmaceutical industry as a pharmaceutical intermediate. 5-Fluoro-2-Oxindole is an intermediate in the synthesis of Sunitinib Malate (CAS: 341031-54-7). Sunitinib Malate is a kind of novel oral multi-targeted anticancer drugs and belongs to multi-targeted tyrosine kinase inhibitor with its trade name being “Suntent”. It was successfully developed by Pfizer Company and has dual anti-tumor effect. Moreover, it is the only therapeutic drug which can go beyond the 2-year survival period of advanced kidney cancer and plays a central role in the field of carcinoma and gastrointestinal stromal tumor therapeutic areas. It entered into market in February 2006 in the United States. This drug was the first anti-cancer drug which was approved by the US FDA and can simultaneously treat two diseases.

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