Chemical Properties:
Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moistureRuifu Chemical Supply Febuxostat Related Intermediates: Febuxostat CAS 144060-53-7 Ethyl 2-Chloroacetoacetate CAS 609-15-4 4-Hydroxythiobenzamide CAS 25984-63-8 Ethyl 2-(3-Cyano-4-Hydroxyphenyl)-4-Methyl-1,3-Thiazole-5-Carboxylate CAS 161798-02-3 Ethyl 2-(3-Cyano-4-Isobutoxyphenyl)-4-Methyl-5-Thiazolecarboxylate CAS 160844-75-7 Ethyl 2-(3-Formyl-4-Hydroxyphenyl)-4-Methylthiazole-5-Carboxylate CAS 161798-01-2 Ethyl 2-(3-Formyl-4-Isobutoxyphenyl)-4-Methylthiazole-5-Carboxylate CAS 161798-03-4 Ethyl 2-(4-Hydroxyphenyl)-4-Methylthiazole-5-Carboxylate CAS 161797-99-5| Item | Specifications |
| Appearance | White or Off-White Powder |
| Identification | HPLC, NMR; LC-MS |
| Related Substances | |
| Individual Impurity | <0.50% |
| Total Impurities | <1.00% |
| Loss on Drying | <0.50% |
| Residue on Ignition | <0.20% |
| Heavy Metals | <10ppm |
| Purity / Analysis Method | >99.0% (HPLC) |
| Test Standard | Enterprise Standard |
| Usage | Intermediate of Febuxostat (CAS: 144060-53-7) |
Description:
Specifications:
Package & Storage:
| Chemical Name | Ethyl 2-(3-Cyano-4-Isobutoxyphenyl)-4-Methyl-5-Thiazolecarboxylate |
| Synonyms | Febuxostat Ethyl Ester; Febuxostat Ethyl Ester Impurity; Febuxostat Impurity 15; Ethyl 2-(3-Cyano-4-Isobutoxyphenyl)-4-Methylthiazole-5-Carboxylate; 2-(3-Cyano-4-Isobutoxyphenyl)-4-Methyl-5-Thiazolecarboxylic Acid Ethyl Ester |
| CAS Number | 160844-75-7 |
| CAT Number | RF-PI1857 |
| Stock Status | In Stock, Production Scale Up to Tons |
| Molecular Formula | C18H20N2O3S |
| Molecular Weight | 344.43 |
| Melting Point | 174.0 to 178.0℃ |
| Density | 1.22 |
| Brand | Ruifu Chemical |
Advantages:
FAQ:
Application:
Ethyl 2-(3-Cyano-4-Isobutoxyphenyl)-4-Methyl-5-Thiazolecarboxylate (CAS: 160844-75-7) is an intermediate or impurity of Febuxostat (CAS: 144060-53-7), a xanthine oxidase/xanthine dehydrogenase inhibitor. Used for treatment of hyperuricemia and chronic gout. 40-120 mg/day Febuxostat was proven effective in lowering serum urate levels when administered to manage hyperuricemia in patients with gout.
