Fmoc-Trp(Boc)-OH CAS 143824-78-6 Purity >98.5% (HPLC) Factory

Chemical Name: Fmoc-Trp(Boc)-OH Synonyms: Nα-Fmoc-N(in)-Boc-L-Tryptophan CAS: 143824-78-6 Purity: >98.5% (HPLC) Appearance: White to Off-White Powder Fmoc-Amino Acids, High Quality Contact: Dr. Alvin Huang Mobile/Wechat/WhatsApp: +86-15026746401 E-Mail: alvin@ruifuchem.com

Products Details

Chemical Properties:

Package: Fluorinated Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement. Storage Condition: Store in sealed containers at cool and dry (2~8℃) warehouse away from incompatible substances. Protect from light and moisture.Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of Fmoc-Trp(Boc)-OH (CAS: 143824-78-6) with high quality. Ruifu Chemical supplys a series of amino acids. We can provide worldwide delivery, competitive price, small and bulk quantities available. Purchase Fmoc-Trp(Boc)-OH, Please contact: alvin@ruifuchem.com

Description:

Package & Storage:

Chemical Name Fmoc-Trp(Boc)-OH  
Synonyms Fmoc-L-Trp(Boc)-OH; Nα-Fmoc-N(in)-Boc-L-Tryptophan; N(in)-Boc-Nα-Fmoc-L-Tryptophan; N(alpha)-Fmoc-N(in)-Boc-L-Tryptophan; 1-Boc-N-Fmoc-L-Tryptophan; Fmoc-Tryptophan(Boc)-OH; N-(9-fluorenyl)methoxycarbonyl-Trp(Boc)-OH; Nα-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N1-tert-Butoxycarbonyl-L-Tryptophan
Stock Status In Stock, Production Capacity 20 Tons per Month
CAS Number 143824-78-6
Molecular Formula C31H30N2O6
Molecular Weight 526.59 g/mol
Melting Point 86.0~93.0℃ 
Density 1.28±0.10 g/cm3 
Sensitive Hygroscopic. Moisture Sensitive
Storage Temp.  Cool & Dry Place (2~8℃) 
COA & MSDS Available
Category   Fmoc-Amino Acids 
Brand Ruifu Chemical

Advantages:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com  15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals. Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc. Advantages? Superior quality, affordable price, professional services and technical support, fast delivery. Quality AssuranceStrict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc. SamplesMost products provide free samples for quality evaluation, shipping cost should be paid by customers. Factory AuditFactory audit welcome. Please make an appointment in advance. MOQ? No MOQ. Small order is acceptable. Delivery Time? If within stock, three days delivery guaranteed. TransportationBy Express (FedEx, DHL), by Air, by Sea. Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided. Custom SynthesisCan provide custom synthesis services to best fit your research needs. Payment TermsProforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

FAQ:

Stable Supply: Maintain reasonable stock    

Professional Service: One stop purchasing service

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

Fast Delivery: If within stock, three days delivery guaranteed

High Quality: Established a complete quality assurance system

Sufficient Capacity: Sufficient facilities and technicians

OEM Package: Custom package and label available

Specifications:

Items Inspection Standards Results
Appearance White to Off-White Powder  White Powder
Specific Rotation [α]20/D -20.0°±4.0° (C=1 in DMF) -20.4°
Melting Point 86.0~93.0℃ 86.2~90.5℃
TLC ≥98.0% >98.0%
Residual Solvents Indicate the Last Solvent Used  Ethyl Acetate, Hexane 
Kaiser Test <0.05% <0.05%
Water by Karl Fischer  <1.00% 0.41%
Fmoc-β-Ala-OH <0.50% Complies
Optical Purity <0.30% D-Enantiomer 0.19%
Clarity of Solution 0.3 gram in 2ml DMF Clear Solution Complies
Purity / Analysis Method >98.5% (HPLC)  99.4% 
300 MHz NMR Spectrum 1H Conforms to Structure Complies         
Infrared Spectrum Conforms to Structure Complies      
Conclusion The product has been tested & complies with the given specifications

143824-78-6 - Risk and Safety:

Application:

Risk Codes R36/37/38 - Irritating to eyes, respiratory system and skin. R51/53 - Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. R43 - May cause sensitization by skin contact Safety Description S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S27 - Take off immediately all contaminated clothing. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. S37 - Wear suitable gloves. S24 - Avoid contact with skin. UN IDs 3077 WGK Germany 3 FLUKA BRAND F CODES 10-21 HS Code 2922491990 Hazard Class 9Fmoc-Trp(Boc)-OH (CAS: 143824-78-6), Fmoc-amino acids, used in peptide synthesis, used as an organic synthesis intermediate, pharmaceutical intermediate, biochemical reagent or chemical reagent. Fmoc-Trp(Boc)-OH is a very useful synthetic intermediate. It is used to prepare Trp containing-peptides. Fmoc-Trp(Boc)-OH can be used for the synthesis of analogs of glucagon-like peptide-1 (GLP-1) for the treatment of type 2 diabetes and various peptides by Fmoc solid phase peptide synthesis (SPPS). The use of this N-in-Boc protected derivative overcomes most of the problems associated with the preparation of Trp containing-peptides by Fmoc SPPS. Cleavage with TFA generates an N-in-carboxy indole which protects the Trp from alkylation [1, 2, 3] and sulfonation [1, 4, 5, 6, 7]. The N-in-carboxy group is removed under aqueous conditions during normal work-up of the peptide. 

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