Chemical Properties:
Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement. Storage Condition: Store in a tightly closed container. Store in a cool, dry and well-ventilated warehouse away from incompatible substances. Protect from light and moisture. Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery. Commercial Supply Nafamostat Mesylate (CAS: 82956-11-4) Related Intermediates| 4-Guanidinobenzoic Acid Hydrochloride | CAS: 42823-46-1 |
| 6-Bromo-2-Naphthol | CAS: 15231-91-1 |
| 6-Cyano-2-Naphthol | CAS: 52927-22-7 |
| 6-Amidino-2-Naphthol Methanesulfonate | CAS: 82957-06-0 |
| N,N′-Dicyclohexylcarbodiimide (DCC) | CAS: 538-75-0 |
| 4-Dimethylaminopyridine (DMAP) | CAS: 1122-58-3 |
| Item | Specifications |
| Appearance | White or Off-White Crystalline Powder |
| Purity | ≥99.0% |
| Melting Point | 280.0~285.0℃ |
| Moisture (K.F) | ≤0.50% |
| Residue on Ignition | ≤0.20% |
| Single Impurity | ≤0.50% |
| Total Impurities | ≤1.00% |
| Heavy Metals (Pb) | ≤5ppm |
| Infrared Spectrum | Consistent with Structure |
| Test Standard | Enterprise Standard |
| Usage | Nafamostat Mesylate and Camostat Mesilate Intermediates |
Description:
Specifications:
Package & Storage:
| Chemical Name | 4-Guanidinobenzoic Acid Hydrochloride |
| Synonyms | 4-Guanidinobenzoic Acid HCl; N-(4-Carboxyphenyl)Guanidine Hydrochloride |
| CAS Number | 42823-46-1 |
| Stock Status | In Stock, Production Scale Up to Tons |
| Molecular Formula | C8H10ClN3O2 |
| Molecular Weight | 215.64 |
| Solubility in Water | Soluble in Water |
| Melting Point | 280.0~285.0℃ |
| Brand | Ruifu Chemical |
Advantages:
FAQ:
Stable Supply: Maintain reasonable stock
Professional Service: One stop purchasing service
Technical Support: Technology solution available
Custom Synthesis Service: Ranged from grams to kilos
Fast Delivery: If within stock, three days delivery guaranteed
High Quality: Established a complete quality assurance system
42823-46-1 - Risk and Safety:
Safety Description 24/25 - Avoid contact with skin and eyes. WGK Germany 3 FLUKA BRAND F CODES 10Sufficient Capacity: Sufficient facilities and technicians
OEM Package: Custom package and label available
42823-46-1 - Application:
Nafamostat Mesylate (CAS: 82956-11-4), an anti-pancreatitis drug was prepared from 4-Guanidinobenzoic Acid Hydrochloride (CAS: 42823-46-1) and 6-Amidino-2-naphthol Methanesulfonate (CAS: 82957-06-0) in the presence of DCC (CAS: 538-75-0) with DMAP (CAS: 1122-58-3)as catalyst with an overall yield of about 28%. 6-Amidino-2-naphthol Methanesulfonate (CAS: 82957-06-0) was prepared from 6-Bromo-2-naphthol (CAS: 15231-91-1) by cyanidation,addition,aminolysis and salt formation. Camostat Mesilate (CAS: 59721-29-8), a drug for pancreatitis treatment was prepared from p-guanidinobenzoic acid hydrochloride and N,N-dimethylcarbamoylmethyl-p-hydroxyphenylacetate in the presence of DCC(N,N-Dicyclohexylcarbodiimide, CAS: 538-75-0) using DMAP (4-Dimethylaminopyridine, CAS: 1122-58-3) as catalyst. p-Guanidinobenzoic Acid Hydrochloride (CAS: 42823-46-1) was prepared from p-aminobenzoic acid and cyanamide by optimization of reaction conditions.This process is simple with easily available starting materials,which is suitable for industrial production.