Chemical Properties:
Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moistureManufacturer Supply Related Intermediates 5-Cyanoindole CAS 15861-24-2 3-(4-Chlorobutyl)-5-Cyanoindole CAS 143612-79-7 Ethyl 5-Nitrobenzofuran-2-Carboxylate CAS 69604-00-8 Ethyl 5-Aminobenzofuran-2-Carboxylate CAS 174775-48-5 5-(Piperazin-1-yl)benzofuran-2-Carboxamide CAS 183288-46-2 CAS 163521-08-2| Item | Specifications |
| Appearance | Off-White to Light Yellow Powder |
| Purity / Analysis Method | >99.0% (HPLC) |
| Melting Point | 98.0~102.0℃ |
| Moisture (K.F) | ≤0.50% |
| Single Impurity | ≤0.50% |
| Total Impurities | <1.00% |
| Test Standard | Enterprise Standard |
| Usage | Intermediate of API (CAS: 163521-08-2) |
Description:
Specifications:
Package & Storage:
| Chemical Name | 3-(4-Chlorobutyl)-5-Cyanoindole |
| Synonyms | 3-(4-Chlorobutyl)-1H-Indole-5-Carbonitrile; 3-(4-Chlorobutyl)indole-5-Carbonitrile |
| CAS Number | 143612-79-7 |
| CAT Number | RF-PI1494 |
| Stock Status | In Stock, Production Scale Up to Tons |
| Molecular Formula | C13H13ClN2 |
| Molecular Weight | 232.71 |
| Brand | Ruifu Chemical |
Advantages:
FAQ:
Application:
3-(4-Chlorobutyl)-5-Cyanoindole (CAS: 143612-79-7) can be obtained by acylation reaction and reduction reaction of 5-Cyanoindole (CAS: 15861-24-2) and 4-Chlorobutyryl Chloride (CAS: 4635-59-0). 3-(4-Chlorobutyl)-5-Cyanoindole is a key intermediate in the synthesis of API (CAS: 163521-08-2). In January 2011, the U.S. FDA approved (CAS: 163521-08-2) for the treatment of major depressive disorder (MDD). (CAS: 163521-08-2) is a novel antidepressant agent that combines potent serotonin reuptake inhibition (IC50=0.2 nM) with high affinity for 5-HT1A receptors (IC50=0.5 nM)and partial 5-HT1A receptor agonist functional activity. (CAS: 163521-08-2) has good selectivity over other monoamine receptors.
