3,5-Bis(trifluoromethyl)phenylacetic Acid CAS 85068-33-3 Purity >99.0% (HPLC) Netupitant Intermediate

Chemical Name: 3,5-Bis(trifluoromethyl)phenylacetic Acid  CAS: 85068-33-3 Purity: ≥99.0% (HPLC) Appearance: White or Off-White Crystalline Powder  Intermediate of Netupitant (CAS: 290297-26-6)  High Quality, Commercial Production E-Mail: alvin@ruifuchem.com

Products Details

Chemical Properties:

Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement. Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture.Manufacturer Supply With High Quality, Commercial Production  Chemical Name: 3,5-Bis(trifluoromethyl)phenylacetic Acid  CAS: 85068-33-3
Item Specifications
Appearance White or Off-White Crystalline Powder
Purity / Analysis Method ≥99.0% (HPLC) 
Loss on Drying ≤1.0%
Total Impurities ≤1.0%
Test Standard Enterprise Standard
Usage Intermediate of Netupitant (CAS: 290297-26-6)

Description:

Specifications:

Package & Storage:

Chemical Name 3,5-Bis(trifluoromethyl)phenylacetic Acid
Synonyms 2-[3,5-Di(trifluoromethyl)phenyl]acetic Acid
CAS Number 85068-33-3
CAT Number RF-PI1197
Stock Status In Stock, Production Scale Up to Hundreds of Kilograms
Molecular Formula C10H6F6O2
Molecular Weight 272.14
Melting Point 121.0~123.0℃ (lit.)
Brand Ruifu Chemical

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Application:

3,5-Bis(trifluoromethyl)phenylacetic Acid (CAS: 85068-33-3) is mainly used in pharmaceutical industry as a pharmaceutical intermediate. 3,5-Bis(trifluoromethyl)phenylacetic Acid can be used as an intermediate of Netupitant (CAS: 290297-26-6), chemical name 2-[3,5-bis(trifluoromethyl)phenyl]-N,2-dimethyl-N-[4-(2-methylphenyl)-6-(4-methylpiperazin-1-yl)pyridin-3-yl]propanamide. Netupitant, originally developed by Helsinn Healthcare and later licensed to Eisai, Inc., was approved in the USA in October 2014 for the treatment of chemotherapy-induced nausea and emesis. 

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