Ethyl 2-Chloroacetoacetate CAS 609-15-4 Purity >99.0% (GC) Febuxostat Intermediate Factory

Chemical Name: Ethyl 2-Chloroacetoacetate  CAS: 609-15-4 Purity: >99.0% (GC)   Appearance: Colorless to Light Yellow Clear Liquid Intermediate of Febuxostat (CAS: 144060-53-7) High Quality, Commercial Production E-Mail: alvin@ruifuchem.com

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Package: Fluorinated Bottle, 25kg/Barrel, or according to customer's requirement Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moistureRuifu Chemical Supply Febuxostat Related Intermediates: Febuxostat CAS 144060-53-7 Ethyl 2-Chloroacetoacetate CAS 609-15-4 4-Hydroxythiobenzamide CAS 25984-63-8 Ethyl 2-(3-Cyano-4-Hydroxyphenyl)-4-Methyl-1,3-Thiazole-5-Carboxylate CAS 161798-02-3 Ethyl 2-(3-Cyano-4-Isobutoxyphenyl)-4-Methyl-5-Thiazolecarboxylate CAS 160844-75-7 Ethyl 2-(3-Formyl-4-Hydroxyphenyl)-4-Methylthiazole-5-Carboxylate CAS 161798-01-2 Ethyl 2-(3-Formyl-4-Isobutoxyphenyl)-4-Methylthiazole-5-Carboxylate CAS 161798-03-4 Ethyl 2-(4-Hydroxyphenyl)-4-Methylthiazole-5-Carboxylate CAS 161797-99-5
Item Specifications
Appearance Colorless to Light Yellow Clear Liquid
Purity / Analysis Method >99.0% (GC)  
1 H NMR Spectrum Consistent With Structure
Total Impurities <1.00%
Test Standard Enterprise Standard
Usage Intermediate of Febuxostat (CAS: 144060-53-7)

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Package & Storage:

Chemical Name Ethyl 2-Chloroacetoacetate
Synonyms 2-Chloroacetoacetic Acid Ethyl Ester; Ethyl 2-Chloro-3-Oxobutyrate
CAS Number 609-15-4
CAT Number RF-PI1854
Stock Status In Stock, Production Scale Up to Tons
Molecular Formula C6H9ClO3
Molecular Weight 164.59
Melting Point  -80℃
Boiling Point  107℃/14 mmHg (lit.)
Density  1.19 g/mL at 25℃(lit.)
Refractive Index n20/D 1.441 (lit.)
Brand Ruifu Chemical

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Application:

Ethyl 2-Chloroacetoacetate (CAS: 609-15-4) is an important intermediate of Febuxostat (CAS: 144060-53-7). Febuxostat is a xanthine oxidase inhibitor, clinically used to treat hyperuricemia (gout). It is a new and highly effective selective inhibitor of non-purine xanthine oxidase. Xanthine oxidase is the key enzyme to promote uric acid production. Febuxosutan can reduce the uric acid level in the blood of patients with hyperuricemia and gout. Clinical studies have shown that the drug is safe and effective. The drug is metabolized through the liver and does not rely on renal excretion. 

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