Chemical Properties:
Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer's requirement. Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.Manufacturer Supply with High Purity and Stable Quality Chemical Name: Entecavir CAS: 142217-69-4 Antiviral drug used in the treatment of Hepatitis B Infection API High Quality, Commercial Production| Item | Specifications |
| Appearance | White Crystalline Powder |
| Identification IR | The infraed absorption spectrum of the test sample must be concordant with the reference standard |
| Identification HPLC | The retention time of the test sample corresponds to that of the reference standard |
| pH | 5.5~7.5 |
| Specific Optical Rotation | +24.0°-+28.0° (DMF: MeOH=1:1 C=1%) |
| Related Substances | |
| Total Impurities | ≤0.30% |
| Maximum Single Impurity | ≤0.10% |
| Enantiomer | ≤0.20% |
| Residual Solvents | |
| Methanol | ≤0.30% |
| Dichloromethane | ≤0.06% |
| n-Hexane | ≤0.029% |
| Tetrahydrofuran | ≤0.072% |
| N,N-Dimethylformamide | ≤0.088% |
| Toluene | ≤0.089% |
| Water Content | 5.8%~6.5% |
| Residue on Ignition | ≤0.10% |
| Heavy Metals | ≤20ppm |
| Assay | 98.0%~102.0% (C12H15N5O3 calculated on anhydrous basis) |
| Particle Size | D90: ≤100µm |
| Test Standard | Enterprise Standard |
| Usage | API, Antiviral drug used in the treatment of Hepatitis B Infection |
Description:
Specifications:
Package & Storage:
| Chemical Name | Entecavir |
| Synonyms | 2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one |
| CAS Number | 142217-69-4 |
| CAT Number | RF-API80 |
| Stock Status | In Stock, Production Scale Up to Hundreds of Kilograms |
| Molecular Formula | C12H15N5O3 |
| Molecular Weight | 277.28 |
| Melting Point | 249.0~252.0℃ |
| Brand | Ruifu Chemical |
Advantages:
FAQ:
Application:
Entecavir is a new generation of guanine nucleoside analogues oral medicine for treatment of Hepatitis B Virus (HBV) infection, mainly for the treatment of adult patients with viral replication activity and serum transaminase continued to increase, or liver tissue for pathological activity of chronic hepatitis B, is currently down virus the fastest and the most powerful, the mutation rate lowest nucleoside analogues. Data show that different in patients with chronic hepatitis B, including nucleoside naive and nucleoside treated and liver cirrhosis patients, using well entecavir tablets in the treatment can control the disease rapidly and easily reach the treatment of reality end, namely the hepatitis B virus unmeasured; through adherence to treatment, a considerable portion of patients can be arrived at the end of treatment satisfaction, namely e antigen serology conversion, some patients can even reach the ideal for the treatment of end, namely surface antigen negative.
