Chemical Properties:
Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer's requirement. Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.Manufacturer with High Purity and Stable Quality Chemical Name: Doxorubicin Hydrochloride CAS: 25316-40-9 Antitumor Antibiotic Agent. Inhibits DNA Topoisomerase II API High Quality, Commercial Production| Item | Specifications |
| Appearance | Orange-Red or Red Crystalline Powder; No visible evidence of contamination by foreign matter |
| Solubility | Soluble in water and methanol; slightly soluble in ethanol; practically insoluble in acetone |
| Identification A | IR spectrum corresponds to the IR spectrum of the reference standard |
| Identification B | The retention time of the doxorubicin peak in the chromatogram of the Assay preparation corresponds to that in the chromatogram of the Standard preparation, as obtained in the Assay. |
| pH | 4.0~5.5 |
| Water Content | ≤4.0% |
| Related Substances | |
| Impurity A (Doxorubicinol) | ≤0.50% |
| Any Other Unknown Impurity | ≤0.20% |
| Total Unknown Impurities | ≤0.50% |
| Total Impurities | ≤1.0% |
| Assay | 98.0%~102.0% of C27H30ClNO11 calculated on the anhydrous, solvent-free basis |
| Residual Solvents | |
| Acetone | ≤0.50% |
| Acetone + Ethanol | ≤2.5% |
| Methanol | ≤0.30% |
| Dichloromethane | ≤0.06% |
| Test Standard | United States Pharmacopeia (USP) Reference Standard |
| Usage | Active Pharmaceutical Ingredient (API) |
Description:
Specifications:
Package & Storage:
| Chemical Name | Doxorubicin Hydrochloride |
| Synonyms | Doxorubicin HCl; Adriamycin HCL; Hydroxydaunorubicin Hydrochloride |
| CAS Number | 25316-40-9 |
| CAT Number | RF-API38 |
| Stock Status | In Stock, Production Scale Up to Tons |
| Molecular Formula | C27H30ClNO11 |
| Molecular Weight | 579.98 |
| Brand | Ruifu Chemical |
Advantages:
FAQ:
Application:
Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of Doxorubicin Hydrochloride (CAS: 25316-40-9) with high quality. Doxorubicin hydrochloride, a cytotoxic anthracycline antibiotic, is an anti-cancer chemotherapy agent. Doxorubicin hydrochloride is a potent human DNA topoisomerase I and topoisomerase II inhibitor with IC50s of 0.8 μM and 2.67 μM, respectively. Doxorubicin hydrochloride induces apoptosis and autophagy. Doxorubicin is a potent antitumour agent active against a wide spectrum of malignancies, including leukaemias, sarcomas, breast cancer, small cell lung cancer and ovarian cancer.
