Chemical Properties:
Package: Bottle, Aluminum foil bag, 25kg/Cardboard Drum, or according to customer's requirement. Storage Condition: Store in sealed containers at cool and dry place. Protect from light and moisture. Incompatible with strong oxidizing agents.Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of Naproxen (CAS: 22204-53-1) with high quality. We can provide COA, worldwide delivery, small and bulk quantities available. If you are interested in this product, please send detailed information includes CAS number, product name, quantity to us. Please contact: alvin@ruifuchem.com| Item | Specifications |
| Appearance | White to Off-White Crystalline Powder |
| Purity / Analysis Method | >99.0% (HPLC) |
| Purity / Analysis Method | >99.0% (Neutralization Titration) |
| Melting Point | 154.0~158.0℃ |
| Specific Rotation [α]20/D | +83.0° to +89.5° |
| Loss on Drying | <0.50% |
| Residue on Ignition | <0.20% |
| Heavy Metals | <0.002% |
| Related Substances | |
| Single Impurity | <0.50% |
| Total Impurities | <1.00% |
| Infrared Spectrum | Conforms to Structure |
| Test Standard | Enterprise Standard |
| Usage | Active Pharmaceutical Ingredients (API) & Intermediates |
Description:
Specifications:
Package & Storage:
| Chemical Name | (S)-(+)-2-(6-Methoxy-2-Naphthyl)propionic Acid |
| Synonyms | Naproxen; (S)-Naproxen; (S)-(+)-Naproxene; (S)-(+)-6-Methoxy-α-Methyl-2-Naphthaleneacetic Acid; (+)-6-Methoxy-alpha-Methyl-2-Naphthaleneacetic Acid |
| CAS Number | 22204-53-1 |
| CAT Number | RF2890 |
| Stock Status | In Stock, ProductionProduction Capacity 1000 Tons per Year |
| Molecular Formula | C14H14O3 |
| Molecular Weight | 230.26 |
| Melting Point | 154.0~158.0℃ |
| Storage & Sensitivity | Light Sensitive. Ambient Temperatures |
| Solubility | Practically Insoluble in Water. Soluble in Ethanol (96%) and in Methanol |
| Hazard Class | 6.1(b) |
| Packing Group | III |
| HS Code | 29189900 |
| Brand | Ruifu Chemical |
Advantages:
How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals. Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc. Advantages? Superior quality, affordable price, professional services and technical support, fast delivery. Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc. Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers. Factory Audit? Factory audit welcome. Please make an appointment in advance. MOQ? No MOQ. Small order is acceptable. Delivery Time? If within stock, three days delivery guaranteed. Transportation? By Express (FedEx, DHL), by Air, by Sea. Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided. Custom Synthesis? Can provide custom synthesis services to best fit your research needs. Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.FAQ:
Stable Supply: Maintain reasonable stock
Professional Service: One stop purchasing service
Technical Support: Technology solution available
Custom Synthesis Service: Ranged from grams to kilos
Fast Delivery: If within stock, three days delivery guaranteed
High Quality: Established a complete quality assurance system
Application:
Naproxen (CAS: 22204-53-1) is a non-steroidal anti-inflammatory drug, it is a PG synthase inhibitor, which can inhibit prostaglandin synthetase, it has significant analgesic and antipyretic effects, oral absorption is rapid and complete, 2 to 4 hours after a dose ,plasma concentration reaches the peak, in the blood, more than 99% is bound to plasma proteins, t1/2 is 13 to 14 hours, about 95% is discharged from the urine with the prototype and metabolites. It is clinically used For the treatment of rheumatic and rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, gout, arthritis, tenosynovitis.it can also be used to alleviate pain caused by musculoskeletal sprains, contusions,damages and dysmenorrhea. But it should be noted that like other non-steroidal anti-inflammatory drugs, the same serious gastrointestinal adverse reactions could occur at any time while taking naproxen during treatment, so the active gastroduodenal ulcer patients are hanged, other gastrointestinal tract disease patients should take this drug under close medical supervision. Naproxen is synthesized from 2-methoxynaphthalene and the (+)-isomer obtained by resolution with cinchonidine (61). It was introduced in the United States in 1976 and, as a generic drug, has consistently been among the more popular NSAIDs. It is marketed as the S-(+)-enantiomer, but interestingly, the sodium salt of the (-)-isomer also is on the market as Anaprox. As an inhibitor of prostaglandin biosynthesis, it is 12 times more potent than aspirin, 10 times more potent than phenylbutazone, three to four times more potent than ibuprofen, and four times times more potent than fenoprofen, but it is approximately 300 times less potent than indomethacin.Sufficient Capacity: Sufficient facilities and technicians
OEM Package: Custom package and label available