Chemical Properties:
Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement. Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture.Manufacturer Supply With High Quality, Commercial Production Chemical Name: Diphenylphosphoryl Azide CAS: 26386-88-9Item | Specifications |
Appearance | Colorless to Light Yellow Liquid |
Purity / Analysis Method | >99.0% (GC) |
Single Impurity | <0.50% |
Residual Solvents | <2.00% |
Test Standard | Enterprise Standard |
Usage | Pharmaceutical Intermediates |
Description:
Specifications:
Package & Storage:
Chemical Name | Diphenylphosphoryl Azide |
Synonyms | DPPA |
CAS Number | 26386-88-9 |
CAT Number | RF-PI1165 |
Stock Status | In Stock, Production Scale Up to Tons |
Molecular Formula | C12H10N3O3P |
Molecular Weight | 275.20 |
Boiling Point | 157℃/0.17 mmHg (lit.) |
Density | 1.277 g/mL at 25℃ (lit.) |
Refractive Index | n20/D 1.551 (lit.) |
Solubility in Water | Decomposes in Contact With Water, Insoluble |
Solubility | Very Soluble in Acetone, Dimethylformamide, Toluene |
Brand | Ruifu Chemical |
Advantages:
FAQ:
Application:
Diphenylphosphoryl Azide (DPPA) (CAS: 26386-88-9) is a well-known azide reagent used in peptide couplings, curtius rearrangements, and Mitsunobu inversions-is often encountered in pharmaceutical process development because it enables the most direct route to a desired product. DPPA acts as a reagent for the synthesis of peptides and phosphoramidates by reacting with amines. DPPA is used for peptide coupling and 1,3-dipole cycloaddition reactions. It is also used to prepare amino acid copolymers. DPPA is widely used in organic synthesis, pharmaceutical synthesis and peptide synthesis. Azide reagent for azidinization of alkenes catalyzed by tetraphenoporphyrin-cobalt. It is also used as an activator in the preparation of macrocyclic lactam and aldose reductase inhibitors. It is also an important organophosphorus reagent.