Chemical Properties:
Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer's requirement. Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.Commercial Supply Dapoxetine Hydrochloride and Related Intermediates: 3-Chloropropiophenone CAS: 936-59-4 (S)-3-Amino-3-Phenylpropan-1-ol CAS: 82769-76-4 (S)-3-Amino-3-Phenylpropanoic Acid CAS: 40856-44-8 (R)-Diphenylprolinol CAS: 22348-32-9 (S)-Diphenylprolinol CAS: 112068-01-6 (S)-(-)-3-Chloro-1-Phenyl-1-Propanol CAS: 100306-34-1 Dapoxetine Hydrochloride CAS: 129938-20-1| Item | Specifications |
| Appearance | White to Almost White Crystalline Powder |
| Identification | IR |
| Assay | ≥99.0% |
| Melting Point | 175.0~182.0℃ |
| Loss on Drying | ≤1.0% |
| Residue on Ignition | ≤0.10% |
| Specific Rotation | +126.0°~130.0°(C=1, CH3OH) |
| Heavy Metals | ≤10ppm |
| Chromatographic Impurities | |
| Single Impurity | ≤0.20% |
| Total Impurities | ≤1.0% |
| Residual Solvents | Meets the Requirement |
| Test Standard | Enterprise Standard |
| Usage | API, SSRI Inhibitor for the treatment of Premature Ejaculation (PE) in Men |
Description:
Specifications:
Package & Storage:
| Chemical Name | Dapoxetine Hydrochloride |
| Synonyms | Dapoxetine HCl; LY-210448 Hydrochloride; Priligy; (S)-N,N-Dimethyl-3-(1-naphthyloxy)-1-phenylpropylamine Hydrochloride |
| CAS Number | 129938-20-1 |
| CAT Number | RF-API92 |
| Stock Status | In Stock, Production Scale Up to Hundreds of Kilograms |
| Molecular Formula | C21H23NO·HCl |
| Molecular Weight | 341.88 |
| Storage Temperature | Room Temperature |
| Brand | Ruifu Chemical |
Advantages:
FAQ:
Application:
Dapoxetine Hydrochloride (CAS 129938-20-1) is the first pharmaceutical, a short-acting novel selective serotonin reuptake inhibitor (SSRI) marketed for the treatment of premature ejaculation in men18-64 years old. Premature ejaculation (PE) is the most common male sexual disorder, estimated to affect up to 30% of men. Dapoxetine treatment was generally well tolerated, with low incidences of discontinuation syndrome, sexual dysfunction, and treatment-emergent mood symptoms. Dapoxetine works by inhibiting the serotonin transporter, increasing serotonin's action at the post synaptic cleft, and as a consequence promoting ejaculatory delay. As a member of selective serotonin reuptake inhibitor (SSRI) family, dapoxetine was initially created as an antidepressant. However, unlike other SSRIs, dapoxetine is absorbed and eliminated rapidly in the body. Its fast acting property makes it suitable for the treatment of PE but not as an antidepressant.
