D-Prolinol CAS 68832-13-3 Purity >99.0% (GC) E.E >99.0% Factory High Quality

Chemical Name: D-Prolinol Synonyms: (R)-(-)-Prolinol; H-D-Pro-ol CAS: 68832-13-3 Purity: >99.0% (GC)  E.E: >99.0% Appearance: Colorless Transparent Liquid Amino Acid Derivative, High Quality  Contact: Dr. Alvin Huang Mobile/Wechat/WhatsApp: +86-15026746401 E-Mail: alvin@ruifuchem.com

Products Details

Chemical Properties:

Package: Fluorinated Bottle, 25kg/Drum, or according to customer's requirement. Storage Condition: Store in sealed containers at cool, dry and ventilated warehouse away from incompatible substances. Protect from light and moisture.Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of D-Prolinol (CAS: 68832-13-3) with high quality. Ruifu Chemical supply a series of amino acids derivatives and peptide synthesis reagents. We can provide COA, worldwide delivery, small and bulk quantities available. If you are interested in D-Prolinol, Please contact: alvin@ruifuchem.com
Hazard Codes Xi 3-10-23
Risk Statements 36/37/38  Hazard Note  Irritant/Air Sensitive 
Safety Statements 26-36-24/25-26/36  Hazard Class  IRRITANT
RIDADR  NA 1993 / PGIII HS Code 2922199090
WGK Germany 3  

Description:

Safety Information:

Package & Storage:

Chemical Name D-Prolinol 
Synonyms D(-)Prolinol; (R)-Prolinol; (R)-(-)-Prolinol; (R)-(-)-2-(Hydroxymethyl)pyrrolidine; (R)-(-)-2-Pyrrolidinemethanol; (R)-Pyrrolidin-2-Methanol; (R)-1-Pyrrolidin-2-ylmethanol; H-D-Pro-ol 
Stock Status In Stock, Production Capacity 50 Tons per Month  
CAS Number 68832-13-3
Molecular Formula C5H11NO 
Molecular Weight 101.15  
Boiling Point 74.0~76.0℃/2 mm Hg(lit.)
Flash Point 86℃(186°F)
Sensitive Hygroscopic. Air Sensitive, Moisture Sensitive, Heat Sensitive
Water Solubility  Completely Soluble in Water
Solubility  Very Soluble in Alcohol
Storage Temp.  Sealed in Dry, Room Temperature
COA & MSDS Available
Brand Ruifu Chemical

Advantages:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com  15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals. Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc. Advantages? Superior quality, affordable price, professional services and technical support, fast delivery. Quality AssuranceStrict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc. SamplesMost products provide free samples for quality evaluation, shipping cost should be paid by customers. Factory AuditFactory audit welcome. Please make an appointment in advance. MOQ? No MOQ. Small order is acceptable. Delivery Time? If within stock, three days delivery guaranteed. TransportationBy Express (FedEx, DHL), by Air, by Sea. Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided. Custom SynthesisCan provide custom synthesis services to best fit your research needs. Payment TermsProforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

FAQ:

Stable Supply: Maintain reasonable stock    

Professional Service: One stop purchasing service

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

Fast Delivery: If within stock, three days delivery guaranteed

High Quality: Established a complete quality assurance system

Application:

D-Prolinol (CAS: 68832-13-3), the D-enantiomer of prolinol, is a chiral amino alcohol used as a chiral resolver in organic synthesis. In recent years, with the rapid development of asymmetric catalysis technology, D-Prolinol has become an excellent ligand for metal coordination catalysis, widely used in asymmetric metal alkylation reaction, Michael addition reaction, phase transfer catalysis and other important organic synthesis. D-Prolinol makes use of an intermediate of pharmaceuticals. Synthesis methods: There are two main methods for the synthesis of D-Prolinol: (1) Indirect reduction method: taking D-Proline as raw material, esterification, neutralization, and then reduction with NaBH4; (2) Direct reduction method: D-Proline was directly reduced by AlLiH4. The former process is complicated and the yield is low (42.6%). The latter operation is harsh, low temperature ice bath drops, high cost, deep product color. The author directly reduced D-proline to D-prolinol by using the reduction system of NaBH4 additive I2 (see the figure below), which has low cost, good quality, stable process, simple operation and easy industrialization.

Sufficient Capacity: Sufficient facilities and technicians

OEM Package: Custom package and label available

Specifications:

Item

Inspection Standard

Results

Appearance

Colorless Transparent Liquid

Conforms

D-Prolinol Purity

>99.0% (GC)

99.61%

Boiling Point

74.0~76℃

Conforms

Specific Rotation [α]20/D

-33.0° to -29.0°(C=1, C7H8)

-31.0°

E.E

>99.0%

99.90%

Water (K.F)

<0.50%

0.33%

Refractive Index n20/D

1.483~1.490

Conforms 

Density (20°C) 

1.035~1.040

Conforms 

Infrared Spectrum

Conforms to Structure

Conforms 

Conclusion

This Product by Inspection Accords with the Enterprise Standard

Main Usage

Chiral Amino Alcohols; Chiral Resolving Agents

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