Chemical Properties:
Package: Bottle, Aluminium foil bag, Cardboard Drum, 25kg/Drum, or according to customer's requirement. Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture.Olaparib and Related Intermediates: Olaparib CAS 763113-22-0 2-Fluoro-5-Formylbenzonitrile CAS 218301-22-5 2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoic acid CAS 763114-26-7 1-(Cyclopropylcarbonyl)piperazine Hydrochloride CAS 1021298-67-8 3-Oxo-1,3-Dihydroisobenzofuran-1-Ylphosphonic Acid CAS 61260-15-9| Item | Specifications |
| Appearance | White Powder |
| Purity | ≥99.0% |
| Moisture (K.F) | ≤0.50% |
| Single Impurity | ≤0.50% |
| Total Impurities | ≤1.0% |
| Test Standard | Enterprise Standard |
| Usage | Pharmaceutical Intermediate |
Description:
Specifications:
Package & Storage:
| Chemical Name | 1-(Cyclopropylcarbonyl)piperazine Hydrochloride |
| CAS Number | 1021298-67-8 |
| CAT Number | RF-PI452 |
| Stock Status | In Stock, Production Scale Up to Tons |
| Molecular Formula | C8H14N2O·HCl |
| Molecular Weight | 190.67 |
| Melting Point | 175.0 to 179.0℃ |
| Solubility | Soluble in Water |
| Brand | Ruifu Chemical |
Advantages:
FAQ:
Application:
1-(Cyclopropylcarbonyl)piperazine Hydrochloride (CAS: 1021298-67-8) is used as a pharmaceutical intermediate. It can be used as a intermediate of Olaparib (CAS: 763113-22-0). Olaparib is a potent inhibitor of both PARP-1 and PARP-2 and is strongly sensitive to KB2P cells due to suppression of base excision repair by PARP inhibition. Olaparib was approved in 2014 by FDA for treating advanced ovarian cancer.
