2-((4-Chlorophenyl)acetyl)benzoic Acid CAS 53242-76-5 Azelastine Hydrochloride Intermediate Factory

Chemical Name: 2-((4-Chlorophenyl)acetyl)benzoic Acid  CAS: 53242-76-5 Assay: 98.0~102.0% Appearance: White to Slight White Powder Intermediate of Azelastine Hydrochloride (CAS: 79307-93-0) in the treatment of Asthma and Allergic Rhinitis High Quality, Commercial Production Inquiry: alvin@ruifuchem.com

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Chemical Properties:

Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement. Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture.Manufacturer Supply, High Purity, Commercial Production  Chemical Name: 2-((4-Chlorophenyl)acetyl)benzoic Acid  CAS: 53242-76-5   Intermediate of Azelastine Hydrochloride (CAS: 79307-93-0)  
Item Specifications
Appearance White to Slight White Powder
Assay 98.0~102.0%
Melting Point 139.0 to 141.0℃
Lossing on Drying ≤0.50%
Total Impurities ≤1.0%
Related Substances Single
4-Chloro Phenyl Acetic Acid ≤0.20%
1,2-Benzene Dicarboxylic Acid ≤0.20%
Benzofuran ≤0.20%
Single Unknown Impurities ≤0.50%
Residual Solvents
Toluene ≤890ppm
Ethanol ≤5000ppm
Benzene ≤50ppm
Test Standard Enterprise Standard
Usage Intermediate of Azelastine Hydrochloride (CAS: 79307-93-0)

Description:

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Package & Storage:

Chemical Name 2-((4-Chlorophenyl)acetyl)benzoic Acid
Synonyms 2-[(4-Chlorophenyl)acetyl]benzoic Acid; 2-[2-(4-Chlorophenyl)acetyl]benzoic Acid; Azelastine EP Impurity C
CAS Number 53242-76-5
CAT Number RF-PI454
Stock Status In Stock, Production Scale Up to Tons
Molecular Formula C15H11ClO3
Molecular Weight 274.7
Brand Ruifu Chemical

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Application:

2-((4-Chlorophenyl)acetyl)benzoic Acid (CAS 53242-76-5) is an intermediate of Azelastine Hydrochloride (CAS: 79307-93-0). Azelastine hydrochloridem, is an orally effective antihistamine, is a potent, second-generation, and selective histamine 1 (H1) receptor antagonist. Azelastine hydrochloride can be used for the research of allergic rhinitis, asthma, diabetic hyperlipidemic and SARS-CoV-2. Azelastine, sold under the brand name Optivar among others, is a medication primarily used as a nasal spray to treat allergic rhinitis (hay fever) and as eye drops for allergic conjunctivitis. Other uses may include asthma and skin rashes for which it is taken by mouth. Onset of effects is within minutes when used in the eyes and within an hour when used in the nose. Azelastine was patented in 1971 and came into medical use in 1986. It is available as a generic medication.

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